甲氨蝶呤与子宫动脉栓塞术对剖宫产术后瘢痕妊娠妇女β-HCG、出血量及成功率的比较研究  

Comparative study of methotrexate and uterine arterial embolization in β-HCG,bleeding volume and success rate of women with cesarean scar pregnancy after cesarean section

作　　者：郑云英[1] 张建果[1] 曹春珠 周红丽[1] 王玲[1] 

机构地区：[1]厦门大学附属第一医院妇产科,福建厦门361022

出　　处：《中国生化药物杂志》2015年第11期121-123,共3页Chinese Journal of Biochemical Pharmaceutics

摘　　要：目的探讨比较甲氨蝶呤与子宫动脉栓塞术对剖宫产术后瘢痕妊娠妇女β人绒毛膜促性腺激素(β-human choriogonadotropin,β-HCG)、出血量及成功率的影响。方法收集收治的剖宫产术后瘢痕妊娠患者42例,随机分为对照组和实验组,每组各21例,分别给予相应的治疗,治疗结束后,对所有患者的血清β-HCG、出血量及成功率进行检测。结果治疗后,与对照组比较,实验组患者的血清β-HCG水平较低(P<0.05);实验组患者的出血量较低(P<0.05);实验组患者的成功率较高(P<0.05)。结论与甲氨蝶呤比较,子宫动脉栓塞术能够更显著降低剖宫产术后瘢痕妊娠患者血清β-HCG水平,减少术中出血量,提高治疗的成功率。Objective To explore comparison between methotrexate and uterine arterial embolization in β-HCG,bleeding volume and success rate of women with cesarean scar pregnancy after cesarean section. Methods 42 patients who were diagnosed with cesarean scar pregnancy after cesarean section were collected. All patients were randomly divided into uterine arterial embolization group and methotrexate group,21 cases in each group corresponding treatment were given respectively,after the treatment,the serum levels of β-HCG,bleeding volume and success rate were detected in all patients. Results After treatment,compared with methotrexate group,the serum level of β-HCG was lower in the uterine arterial embolization group,and the difference was statistically significant（ P〈0. 05）; the bleeding volume was lower in the uterine arterial embolization group（ P〈0. 05）; the success rate was higher in the uterine arterial embolization group（ P〈0. 05）. Conclusion Compared with methotrexate,the uterine arterial embolization can significantly reduce the serum level of β-HCG in patients with cesarean scar pregnancy after cesarean section,reduce the amount of bleeding,improve the success rate of treatment.

关 键 词：甲氨蝶呤 子宫动脉栓塞术 剖宫产术后瘢痕妊娠 Β-HCG 出血量 成功率 

分 类 号：R719[医药卫生—妇产科学]