蒙药长松萝的化学成分研究(Ⅱ)  

Chemical Constituents from Usnea longgisima,a Traditional Mongolian Medicine( Ⅱ)

作　　者：拉喜那木吉拉 梁鸿[2] 巴根那[1] 邰巴达拉胡 

机构地区：[1]内蒙古民族大学蒙医药学院,内蒙古通辽028000 [2]北京大学天然药物及仿生药物国家重点实验室/药学院天然药物学系,北京100191

出　　处：《中药材》2015年第12期2541-2542,共2页Journal of Chinese Medicinal Materials

基　　金：国家自然科学基金(811460653);内蒙古民族大学博士科研启动基金(BS26)

摘　　要：目的:研究蒙药长松萝的化学成分。方法:应用多种色谱技术对长松萝进行分离纯化,并通过NMR等波谱方法鉴定化合物的结构。结果:从长松萝乙醇提取物的乙酸乙酯萃取部位分离得到3个化合物,分别鉴定为:4-羟基-2-(2-羟基-4-甲氧基-6-甲基-苯甲酰氧基)-6-甲基苯甲酸(1)、邻苯二甲酸正丁酯(2)、邻苯二甲酸异丁酯(3)。结论:化合物1为新化合物,命名为异去甲环萝酸(isoevernic acid),化合物2、3为首次从长松萝中分离得到。Objective： To study the chemical constituents of traditional Mongolian medicine Usnea longissima. Methods： The compounds were isolated and purified by the methods of solvent extraction and chromatographic technique,and their structures were identified on the basis of the analyses of spectral data. Results： Three compounds were obtained and identified as 4-hydroxy-2-[（ 2-hydroxy-4-methoxy-6-methylbenzoyl） oxy]-6-methylbenzoic acid（ 1）,dibutyl phthalate（ 2） and diisobutyl phthalate（ 3）. Conclusion： Compound 1is a new compound and named as isoevernic acid,compounds 2 and 3 are isolated from Usnea longissima for the first time.

关 键 词：蒙药 长松萝 异去甲环萝酸 

分 类 号：R284.1[医药卫生—中药学] R284.2[医药卫生—中医学]