A_3亚型患者输注A型血液后出现抗-A_1一例  

The appearance of anti-A_1 in an A_3 subtype patient after infusion with A type blood

作　　者：李娜[1] 杨世明[1] 焦琴[1] 穆士杰[1] 

机构地区：[1]第四军医大学唐都医院输血科,陕西西安710038

出　　处：《诊断学理论与实践》2015年第6期519-521,共3页Journal of Diagnostics Concepts & Practice

摘　　要：目的 :分析1例A_3亚型患者输注交叉配血相合血液后出现抗-A_1的情况,探讨ABO血型亚型输血原则。方法:采用微柱凝胶法、试管法及吸收放散等检测方法确定1例A_3亚型患者,按照相容性输血原则,在交叉配血相合的情况下给予A型红细胞输注,6 d后再次输血时复查其血型。结果:患者定型为A3亚型并予输注A型红细胞,过程顺利,无不良反应,但于输血后第6天,患者产生抗-A_1。结论:对于ABO血型亚型患者,建议在非急救用血时选择供者红细胞抗原种类等于或少于患者自身的血液,避免刺激机体产生抗体,以便患者在紧急用血时可有更多选择。Objective： To study the appearance of anti-A1 in an A3 subtype patient after infusion with A type blood and discuss the guidelines of transfusion of ABO subgroup. Methods： Gel microcolumn assay, tube test, absorb-elution test were used to test an A3 subtype patient, who was transfused with A type red blood cell in accordance with the principle of compatible transfusion. Six days after transfusion, the patient was re-tested. Results： The transfusion process was carried out smoothly, however, anti-A1 appeared at the sixth day after transfusion. Conclusions： It is suggested that we should choose the blood having antigens equal or less in number than those in patient＇s own in non-emergency situation, which will not stimulate the body to produce antibodies, thus we will have more choices in emergency condition afterwards.

关 键 词：A3亚型 输血 抗-A1 

分 类 号：R554[医药卫生—血液循环系统疾病]