膳食多不饱和脂肪酸与女性内脏型肥胖的关系  

Relationship between dietary polyunsaturated fatty acids intake and female visceral obesity

作　　者：朱玉凤[1] 张美琳[1] 李萍[1] 常红[1,2] 黄国伟[1] 

机构地区：[1]天津医科大学公共卫生学院营养与食品卫生学系,天津300070 [2]天津医科大学康复与运动医学系

出　　处：《中国慢性病预防与控制》2016年第3期192-195,共4页Chinese Journal of Prevention and Control of Chronic Diseases

基　　金：国家科技支撑计划项目(2012BAI02B02)

摘　　要：目的分析女性内脏型肥胖与膳食多不饱和脂肪酸（PUFA）之间的相关性,为预防女性肥胖提供依据。方法选取2013年在天津市和平区健康体检中心进行健康体检的1 617名女性为调查对象,按照内脏脂肪面积（VFA）的大小,分为内脏脂肪正常组（VFA〈90 cm^2,1 011例）和内脏脂肪肥胖组（VFA≥90 cm^2,606例）。对体检者进行体格检查、实验室生化指标检查和膳食调查,并采用体脂仪测定VFA。应用SPSS 19.0软件及t检验和χ2检验进行统计学分析。应用协方差分析以及logistic回归分析女性VFA与PUFA之间的相关性。结果女性内脏脂肪肥胖组的年龄、体质指数（BMI）、总胆固醇（TC）、甘油三酯（TG）、低密度脂蛋白胆固醇（LDL-C）以及空腹血糖（FPG）均高于内脏脂肪正常组,高密度脂蛋白胆固醇（HDL-C）显著低于内脏脂肪正常组,差异均有统计学意义（P〈0.01）。年龄、BMI、TG、TC、LDL-C和FPG与VFA呈正相关（r值分别为0.479、0.792、0.401、0.300、0.325和0.262,P〈0.01）,HDL-C与VFA呈负相关（r=-0.210,P〈0.01）。随着VFA的升高,膳食n-3 PUFAs的摄入量逐渐减少,趋势性检验差异有统计学意义（P〈0.05）。采用步入法调整年龄、BMI、能量、膳食纤维、饱和脂肪酸、不饱和脂肪酸、体力活动和吸烟饮酒等混杂因素后,最高摄入水平的n-3 PUFAs（OR=0.67,95%CI：0.45~0.98）和n-6 PUFAs（OR=0.65,95%CI：0.44~0.97）是女性内脏型肥胖的保护性因素。未发现n-6/n-3比例与女性内脏型肥胖相关。结论在女性人群中膳食低n-3、n-6 PUFAs摄入水平容易导致体内内脏脂肪蓄积。Objective To analyze the relationship between dietary polyunsaturated fatty acids（PUFA） intake and visceral obesity of females and to provide the basis for preventing female obesity. Methods All 1 617 females were selected as the subjects from the health examination in Health Education and Guidance Center in Heping district of Tianjin in 2013. The investigation was performed with physical examination, laboratory test and dietary questionnaire for all subjects. Body fat analyzer was used to measure the visceral fat area（VFA）. According to VFA, 1 617 subjects were divided into high VFA group（VFA≥90 cm^2, 606cases） and normal VFA group（VFA90 cm^2, 1 011 cases）. Covariance analysis and logistic regression were used to analyze the relationship between female PUFA and UFA with SPSS 19.0 software. Results As compared with normal VFA group, the age, body mass index（BMI）, triglyceride（TG）, total cholesterol（TC）, low-density lipoprotein cholesterol（LDL-C） and fasting plasma glucose（FPG） in high VFA group significantly increased, and high-density lipoprotein cholesterol（HDL-C） in high VFA group significantly decreased（P〈0.01）. Age, BMI, TG, TC, LDL-C and FPG correlated positively with VFA（r values were 0.479, 0.792,0.401, 0.300, 0.325 and 0.262, respectively, P〈0.01）. HDL-C correlated negatively with VFA（r=-0.210, P〈0.01）. The intake of n-3 PUFAs decreased gradually with VFA increasing（P〈0.05）. After adjusting the confounding factors（age, BMI, total energy intake, saturated fatty acids, monounsaturated fatty acids, fiber, physical activity, drinking and smoking）, the highest n-3 PUFAs level（OR=0.67, 95%CI： 0.45-0.98） and n-6 PUFAs level（OR=0.65, 95%CI： 0.44-0.97） were the protective factors of female visceral obesity. There was no significant correlation between n-6/n-3 and female visceral obesity. Conclusion The low dietary n-3 PUFAs and n-6 PUFAs intake levels may increase the accumulation of visceral fat in females.

关 键 词：内脏脂肪面积 多不饱和脂肪酸 内脏型肥胖 

分 类 号：R589.2[医药卫生—内分泌]