苏叶地黄汤对慢性肾功能衰竭患者“微炎症状态”的影响  

Influence of Suye Dihuang Decoction on the "Microinflammation State" of Patients with Chronic Renal Failure

作　　者：孙响波 王霞[2] 于妮娜 

机构地区：[1]青岛市海慈医疗集团,山东青岛266000 [2]即墨市第三人民医院,山东即墨266200

出　　处：《河南中医》2016年第3期545-546,共2页Henan Traditional Chinese Medicine

基　　金：山东省科技发展计划项目(编号:2010G0020214)

摘　　要：目的:观察苏叶地黄汤对慢性肾功能衰竭(chronicrenalfailure,CRF)患者"微炎症状态"的影响。方法:选取2012年3月—2013年8月本院住院和门诊治疗的CRF患者68例,辨证均为脾肾两虚兼湿浊证,所有患者在常规治疗的基础上加用苏叶地黄汤治疗,治疗2个月后观察治疗前后血清白细胞介素-1(IL-1)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)、C-反应蛋白(CRP)的含量变化。结果:治疗后患者血清中IL-1、TNF-α、IL-6、hs-CRP水平均优于治疗前(P<0.05)。结论:苏叶地黄汤能改善CRF患者"微炎症状态"。Objective： To observe the influence of Suye Dihuang Decoction on the ＂ microinflammation state＂ of patients with chronic renal failure（ CRF）. Methods： Totally 68 cases CRF patients hospitalized between March 2012 and August 2013,differentiated as kidney and spleen deficiency complicated with damp turbidity syndrome,were given Suye Dihuang Decoction on the basis of conventional treatment. After 2 months of treatment,the changes in the contents of IL-1,IL-6,TNF-α and CRP were observed. Results： After the treatment,the levels of IL-1,IL-6,TNF-α and CRP were better than these before the treatment. Conclusion： Suye Dihuang Decoction can improve the ＂ microinflammation state＂ of patients with CRF.

关 键 词：慢性肾功能衰竭 “微炎症状态” 苏叶地黄汤 

分 类 号：R277.592.5[医药卫生—中医学]