聚丙烯酸/聚乳酸复合多孔pH响应水凝胶的制备及性能  

Fabrication and Property of pH-Responsive Porous Polyacrylic Acid / Polylactic Acid Composite Hydrogels

作　　者：陈培珍[1] 刘瑞来[1,2] 

机构地区：[1]武夷学院生态与资源工程学院福建省高校绿色化工技术重点实验室,福建武夷山354300 [2]福建师范大学材料科学与工程学院福建省高分子材料与工程重点实验室,福建福州350007

出　　处：《高分子材料科学与工程》2016年第3期173-177,共5页Polymer Materials Science & Engineering

基　　金：国家自然科学基金资助项目(51406141);福建省教育厅(JK2014052;JA13320)

摘　　要：利用电纺制备直径为(2.69±0.63)μm,孔径大小为150 nm×120 nm聚乳酸(PLLA)纳米孔超细纤维。以丙烯酸(AA)为单体,N,N-亚甲基双丙烯酰胺为交联剂,过硫酸钾为引发剂,通过自由基聚合制备聚丙烯酸(PAA)水凝胶。将PLLA纳米孔超细纤维浸泡在上述体系中,通过原位聚合制备PAA/PLLA复合水凝胶,并研究m(AA)∶m(PLLA)对复合水凝胶形貌的影响。致孔剂聚乙二醇(PEG)加入,明显提高纤维孔隙率。与PAA水凝胶相比,PAA/PLLA复合水凝胶pH响应时间大大缩短,且拉伸强度由1.9 MPa增加到5.2 MPa,弹性模量从90.4 MPa增加到108.2 MPa。Polylactic acid （PLLA） ultrafine fibers with diameter of （2.69 ± 0.63）μm and mesopores of 150 nm × 120 nm were prepared by electrospinning. Polyacrylic acid （PAA） hydrogel was prepared through free radical polymerization using acrylic acid （AA） as monomer, N, N ＇-methylene bisacrylamide as crosslinking agent and potassium persulfate as initiator. PAA/PLLA composite hydrogels were fabricated through in-situ polymerization by immersing PLLA ultrafine fibers into AA polymer system. The effects of AA： PLLA mass ratio on the morphology of the hydrogels were studied. The porosity of PLLA fibers is increased by using polyethylene glycol as porogen. Compared with PAA hydrogel, pH-responsive property of PAA/PLLA composite hydrogels is greatly increased. Moreover, the tensile strength and elastic modulus increase from 1.9 MPa to 5.2 MPa and 90.4 MPa to 108.2 MPa, respectively.

关 键 词：聚乳酸 聚丙烯酸 水凝胶 PH响应 多孔 

分 类 号：O632.51[理学—高分子化学]