邻硝基氯苯水解制备邻硝基苯酚的工艺研究  

Study on synthesis of 2-nitrophenol by hydrolysis of o-nitrochlorobenzene

作　　者：陈星[1] 王小丽[1] 陈书鸿[1] 崔政[1] 赖庆轲[1] 李廷真[1] 

机构地区：[1]重庆三峡学院环境与化学工程学院,重庆404100

出　　处：《应用化工》2016年第3期470-471,475,共3页Applied Chemical Industry

基　　金：重庆市科委基金项目(cstc2013jcyj A20007);重庆三峡学院青年基金(14QN23)

摘　　要：以邻硝基氯苯为原料,氢氧化钠为缚酸剂,经高温高压反应得邻硝基苯酚钠,再酸化生成邻硝基苯酚。考察反应压力、氢氧化钠的浓度、氢氧化钠与邻硝基氯苯的摩尔比和反应时间对邻硝基苯酚产率的影响。结果表明,最佳反应条件为:反应压力0.9 MPa,氢氧化钠水溶液的质量分数为10.0%,氢氧化钠与邻硝基氯苯的摩尔比为2.0,反应时间10 h。在此反应条件下,邻硝基苯酚的产率达94.7%。An efficient,simple,and practical method of preparation of 2-nitrophenol has been reported by the active chlorine displacement of o-nitrochlorobenzene in the presence of Na OH with excellent reaction performance. The influence of reaction pressure,the concentration of aqueous sodium hydroxide,the sodium hydroxide to o-nitrochlorobenzene molar ratio and reaction time on o-nitrochlorobenzene yield was investigated. The results showed that the best reactive conditions were reaction pressure 0. 9 MPa,the concentration of aqueous sodium hydroxide solution 10. 0%,the mole ratio of sodium hydroxide and o-nitrochlorobenzene of 2. 0,reaction time 10 h. Under these conditions,the highest yield of 2-nitrophenol was94. 7%.

关 键 词：邻硝基苯酚 邻硝基氯苯 水解 正交实验 

分 类 号：TQ224.7[化学工程—有机化工]