先天性甲状腺功能减低症患儿治疗依从性影响因素分析  

Analysis of the compliance and the influencing factors of the treatments of children with congenital hypothy-roidism

作　　者：阎亚琼[1] 杨建平[2] 白丽霞[2] 张华[2] 白增华[2] 郝丽婷[2] 赵海峰[1] 

机构地区：[1]山西医科大学公共卫生学院营养与食品卫生学教研室,山西省太原030001 [2]山西省妇幼保健院儿保科,山西省太原030013

出　　处：《中国基层医药》2016年第5期667-670,共4页Chinese Journal of Primary Medicine and Pharmacy

基　　金：基金项目：山西省妇幼保健院资助项目（2011-01）

摘　　要：目的分析先天性甲状腺功能减低症（CH）患儿随访治疗的依从性及其影响因素。方法针对231例cH患儿，采用查阅病例的方式收集相关因素，按定期随访治疗分为依从性好与依从性差两组；单因素采用x2检验，多因素分析采用非条件logistic回归分析。结果（1）单因素分析显示：血清促甲状腺激素（TSH）值正常（x2=59．870，P=0．000）、血清游离甲状腺素（n）值正常（x2=6．468，P=0．01）、路途近（x2=16．375，P=0．00）、母亲文化高（0=7．483，P=0．02）、CH患儿（x2=7．483，P=0．04）定期随访治疗的依从性高。（2）多因素Logistic逐步回归分析显示：血清TSH值正常（OR=17．135）、路途近（OR=1．692）、CH诊断（OR=4．028）引入logistic回归模型具有统计学意义（P〈0．05）。结论应针对路途远、母亲文化低、诊断为高TSH血症患儿积极采取措施加强管理，提高CH患儿定期随访治疗的依从性，更好的促进CH患儿的生长及智能发育水平。Objective To analyze the compliance and the influencing factors of the children with congenital hypothyroidism （CH）. Methods 231 children with CH were collected for this study. The questionnaire survey and referring the case were used to collect relative factors. According to regular follow - up treatment, the children were divided into two groups, one group was good compliance and the other One was bad compliance. The results were ana- lyzed by two - independent sample t - test,2 - test and unconditioned logistic regression analysis. Results （ 1 ） Blood TSH （ X2 = 59.870, P = 0.00） and blood FT4 （ X2 = 6.468, P = 0.01 ） were normal, short distance from the hospital （ X2 = 16. 375, P = 0.00）, level of education of their mothers was high （ X2 = 7. 483, P = 0.02 ）, and regular compli- ance treatment of children with CH （ X2 = 7. 483, P = 0. 024 ） was good. （ 2 ） Logistic stepwise regression analysis showed that serum TSH value （ OR = 17. 135 ）, the short distance （ OR = 1. 692） and diagnosis of CH （ OR = 4.028 ） were introduced into the logistic regression model （ all P 〈 0.05 ）. Conclusion It is essential to take measures actively and reinforce the management of children with long distance,low - educated, and the diagnosis of TSH. More- over,enhancing the regular treatment compliance of children with CH is the key to improve the growth and develop- ment status of children with CH.

关 键 词：先天性甲状腺功能减低症 定期随访 依从性 影响因素 

分 类 号：R725.8[医药卫生—儿科]