聚焦超声与布地奈德鼻喷雾剂治疗变应性鼻炎疗效比较  

Comparison of efficacy of focused ultrasound and Budesonide nasal spray in treatment of allergic rhinitis

作　　者：李剑挥[1] 袁永一[1] 王新[1] 刘穹[1] 雷磊[1] 

机构地区：[1]解放军总医院海南分院耳鼻咽喉头颈外科,海南三亚572000

出　　处：《解放军医学院学报》2016年第3期219-221,共3页Academic Journal of Chinese PLA Medical School

基　　金：海南省卫生厅2013年度科研项目(琼卫2013资助-095号)~~

摘　　要：目的通过比较聚焦超声与布地奈德鼻喷雾剂治疗变应性鼻炎的疗效,探讨聚焦超声治疗变应性鼻炎的优越性。方法对2013年10月-2014年9月在解放军总医院海南分院行聚焦超声治疗的变应性鼻炎患者65例进行治疗前后自身比较,并与同期使用布地奈德鼻喷雾剂治疗的变应性鼻炎患者68例进行疗效对比。结果术后随访6个月~1年。聚焦超声组治疗前评分9.12±2.06,治疗后评分4.35±1.27,显效31例（47.69%）,有效28例（43.08%）,无效6例（9.23%）,总有效率90.77%,不良反应6例（9.23%）。布地奈德鼻喷雾剂组治疗前评分8.11±1.97,治疗后评分5.35±1.27,显效22例（32.35%）,有效33例（48.53%）,无效13例（19.12%）,总有效率80.88%,不良反5例（7.35%）。聚焦超声组治疗前后评分差异、两组总有效率差异有统计学意义（P〈0.05）,两组不良反应率差异无统计学意义（P〉0.05）。结论聚焦超声治疗变应性鼻炎疗效稳定,优于布地奈德鼻喷雾剂治疗,且不良反应小、术后恢复快。Objective To investigate the advantages of focused ultrasound in treatment of allergic rhinitis by comparing it with Budesonide nasal spray. Methods The efficacy of 65 allergic rhinitis patients before and after focused ultrasound treatment in our hospital from October 2013 to September 2014 was compared, and the efficacy of 68 allergic rhinitis patients with the use of budesonide nasal spray was compared with the efficacy of focused ultrasound. Results Postoperative follow-up was done for 6 months to 1 year. The score before and after treatment in focused ultrasound group was（9.12±2.06） and（4.35±1.27）, 31 cases were markedly improved（47.69%）, 28 cases improved（43.08%）, and invalid was found in 6 cases（9.23%） with the total effective rate of 90.77%, while 6 cases had adverse reactions（9.23%）. The score before and after treatment in budesonide nasal spray group was（8.11±1.97） and（5.35±1.27）, 22 cases were markedly improved（32.35%）, 33 cases improved（48.53%）, and invalid was found in 13 cases（19.12%） with the total effective rate of 80.88%, while 5 cases had adverse reactions（7.35%）. There were significant differences in score of before and after focused ultrasound treatment and total effective rate between two groups（P 〈0.05）, while there was no significant difference in adverse reaction rate between two groups（P 〉0.05）. Conclusion The focused ultrasound treatment for allergic rhinitis has long-term effectiveness with stability, and its total effective rate is higher than budesonide nasal spray treatment with smaller adverse reaction rate and rapid postoperative recovery.

关 键 词：聚焦超声 布地奈德 变应性鼻炎 

分 类 号：R765.21[医药卫生—耳鼻咽喉科]