基层医院儿童抗菌药物临床应用现状调查  

Investigation on Clinical Use of Antibiotics in Children in Grass-root Hospitals

作　　者：郭雪玲[1] 张万智[1] 程志[1] 

机构地区：[1]安陆市普爱医院,湖北安陆432600

出　　处：《中国执业药师》2016年第3期16-18,51,共4页China Licensed Pharmacist

摘　　要：目的:了解某院儿科抗菌药物使用特点,为抗菌药物合理使用提供参考。方法:从医院信息系统(HIS)中提取2015年1-6月某院儿科抗菌药物使用品种、数量、金额,并计算其使用强度。结果:儿科住院患者抗菌药物用药频度(DDDs)排名前5位的是头孢哌酮钠-他唑巴坦、头孢美唑、氟氯西林、头孢孟多酯和头孢替安,占累计限定日剂量(DDD)构成比的80.61%;门诊患者抗菌药物使用率73.28%,住院患者抗菌药物使用率62.39%;住院患者抗菌药物使用强度为45.14 DDD,静脉滴注是主要给药途径。结论:抗菌药物在儿科的使用率和使用强度高,静脉用药的危害认识不足应该得到社会的关注,从法律层面和技术层面保障儿科患者合理使用抗菌药物。Objective ：To investigate the characteristics of application of antibiotics in the department of pediatrics of a hospital and provide a reference for the rational use of antimicrobial drugs. Methods ： The data on the variety, quantity and cost of antibiotics used in department of pediatrics from January to June 2015 were collected from hospital information system（HIS） for calculation of intensity of use. Results ： Cefoperazone tazobactam, cefmetazole, flucloxacillin, cefamandole esters and cefotiam ranked the first to the fifth of DDDs,which accounted for 80.61% of the cumulative proportions of DDD. The utilization rate of antimicrobial drugs in outpatients was 73.28%, while that in hospitalized patients was 62.39%. The intensity of use of antimicrobial agents in hospitalized patients was 45.14 DDD, while intravenous infusion was the main route of administration.Conclusion ： High utilization rate and the intensity of use of antimicrobial agents were observed in pediatrics,indicating that the lack of understanding of the harm of intravenous infusion should be concerned by the community, and the rational use of antimicrobial drugs in pediatrics should be guaranteed at legal and technical levels.

关 键 词：儿科 抗菌药物 分析 使用强度 

分 类 号：R969.3[医药卫生—药理学]