非官能烯烃不对称环氧化反应研究进展  

Epoxidation reaction of non functionalized alkene

作　　者：李怡然[1] 王亚明[1] 蒋丽红[1] 

机构地区：[1]昆明理工大学化工学院,云南昆明650500

出　　处：《化工科技》2016年第1期72-77,共6页Science & Technology in Chemical Industry

基　　金：国家自然科学基金项目(U1202265)

摘　　要：由于具有光学活性的环氧化物是很多药物、光学材料、天然产物的重要合成中间体,非官能烯烃不对称环氧化反应不断受到人们的关注。虽然人们采取了多种途径来获得手性环氧化物,但对于手性催化剂催化非官能烯烃不对称环氧化仍是化学界的难题。综述了几类手性催化剂如:手性金属卟啉催化剂、手性salen Mn(Ⅲ)催化剂催化非官能烯烃环氧化研究新进展。The epoxides with optical activity are important intermediates of many drugs,optical materials,and natural products.So,the research on epoxidation reaction of functionalized alkene is getting more and more attention.Although people have taken different approaches to obtain chiral epoxide,but for chiral catalyst catalyzing olefin asymmetric epoxidation is still the problem of chemical industry.This paper reviewed several chiral catalyst,such as：Chiral metalloporphyrin catalysts and chiral salen Mn（Ⅲ）catalysts;and summarized their new progress in catalyzing epoxidation of non functional alkene.

关 键 词：手性催化剂 烯烃 环氧化反应 

分 类 号：O643[理学—物理化学]