间苯三酚在急诊胆绞痛治疗中的应用  

Application of phloroglucinol in the treatment of acute biliary colic

作　　者：李影[1] 俞富祥[2] 叶媛媛[1] 林卫红[1] 张若丹[1] 孙洪伟[2] 

机构地区：[1]温州医科大学附属第一医院手术室,浙江温州325015 [2]温州医科大学附属第一医院肝胆外科,浙江温州325015

出　　处：《温州医科大学学报》2016年第3期220-222,共3页Journal of Wenzhou Medical University

基　　金：国家自然科学基金资助项目(81070372);浙江省自然科学基金资助项目(LY12H03005)

摘　　要：目的:评价间苯三酚在急诊胆绞痛治疗中的疗效及安全性。方法:368例急诊胆绞痛患者随机分为治疗组236例,对照组132例。治疗组间苯三酚120 mg加入5%葡萄糖溶液静脉滴注,对照组山莨菪碱10 mg加入5%葡萄糖溶液静脉滴注,2组均联合使用抗生素。观察止痛疗效及不良反应。结果:治疗后1 h内,治疗组的显效率为69.1%,总有效率为91.1%,对照组的显效率为53.0%,总有效率为74.2%,2组比较显效率及总有效率的差异均有统计学意义(均P<0.05)。治疗组和对照组的不良反应发生率分别为0.9%和95.4%,2组比较差异有统计学意义(P<0.05)。结论:间苯三酚治疗急诊胆绞痛比山莨菪碱的疗效更好,不良反应更少。Objective： To analyze the value of phloroglucinol in the treatment of acute biliary colic. Methods： Three hundred and sixty-eight patients with acute biliary colic were randomly divided into two groups, 236 as the treatment group and 132 as the control group. 120 mg phloroglucinol was added in 5% glucose solution through intravenous drip in the treatment group, while 10 mg anisodamine through the same way in the control. Both two groups used associated antibiotics. The anticolic efficacy was analyzed as well as the side effects. Results： One hour after treatment, the excellence rate of the treatment group was 69.1%, while total efficacy rate was 91.1% and the excellence rate of the control group was 53.0%, while total efficacy rate was 74.2%. There was significant difference between the treatment group and the control group（P〈0.05）. The incidence rate of the side effects in the treatment group was 0.9%, while 95.4% in the control. There was significant difference between these two groups（P〈0.05）. Conclusion： As phloroglucinol has better curative effect and fewer side effects in the treatment of acute biliary colic, it is worth of promotion and utilization in the clinical medical treatment.

关 键 词：间苯三酚 胆绞痛 急诊 

分 类 号：R657.4[医药卫生—外科学]