循环microRNA在心血管疾病中的研究进展  

Research Progress Of Circulating MicroRNA In Cardiovascular Diseases

作　　者：黄颖[1] 伍伟锋[2] 韦永强[1] 赵春丽[1] 

机构地区：[1]广西医科大学附属民族医院心内科,南宁市530021 [2]广西医科大学第一附属医院心血管病研究所,南宁市530021

出　　处：《中国分子心脏病学杂志》2016年第1期1613-1616,共4页Molecular Cardiology of China

基　　金：广西医科大学青年科学基金项目(GXMUYSF201304)

摘　　要：micro RNAs(mi RNAs)是一类可调控基因表达的真核生物内源性小分子单链RNA,研究发现mi RNAs可从细胞内释放,广泛而稳定地存在于细胞外液,统称为循环mi RNAs,而多项研究均表明后者与多种心血管病密切相关,是潜在用于疾病诊断的无创性新型生物标志物。本文就循环mi RNAs在心血管疾病方面的研究进展做一综述。Micro RNAs（mi RNAs） is a kind of endogenous small molecule single stranded RNA, which can regulate gene expression. It is found that mi RNAs can be released from the cell,presencing widespread and stably in the extracellular f luid,being called Circulating Micro RNA.A number of studies had indicated that Circulating Micro RNA are closely related to many cardiovascular diseases,The aim of this brief review is to summarize the recent literatures concerning circulating mi RNAs in the cardiovascular diseases.

关 键 词：循环miRNAs 心血管疾病 生物学标志物 

分 类 号：R54[医药卫生—心血管疾病]