腰椎骨髓脂肪与腹部脂肪相关性的前瞻性研究  

Correlation between vertebral bone marrow fat and abdomen fat: a prospective study

作　　者：张晓东[1] 赵银霞[1] 赵文吉[1] 张灵艳[1] 严杰文[1] 郝帅[1] 卢雄光 赵静[1] 李绍林[1] 

机构地区：[1]南方医科大学第三附属医院//广东省骨科研究院,医学影像科,广东广州510630

出　　处：《南方医科大学学报》2016年第2期286-289,共4页Journal of Southern Medical University

摘　　要：目的探讨腰椎骨髓脂肪与腹部脂肪的相关性。方法共68人（男32人,女36人,年龄21~74岁,中位年龄49.5岁）纳入前瞻性研究。1.5T MR采用单体素点分辨波谱法（PRESS）对L3椎体进行波谱采集,计算脂肪比（FF%）;同时行腰椎64排CT检查,用定量CT（QCT）分析软件测量L3相应层面腹部皮下脂肪（SAT）与内脏脂肪（VAT）。男、女按年龄各分为两组（≥50岁和〈50岁）,用SPSS 19.0软件进行统计学分析。结果男性BMI、FF%、VAT及SAT≥50岁组和〈50岁组比较均无显著性差异（P〉0.05）,FF%与BMI、VAT及SAT均无明显相关性（r分别为-0.109、0.034、-0.066,P〉0.05）。女性BMI、FF%、VAT及SAT≥50岁组和〈50岁组比较均有显著性差异（P〈0.05）;女性≥50岁组,FF%与VAT呈明显正相关（r为0.499,P〈0.05）,FF%与SAT无明显相关性（r为0.221,P〉0.05）;女性〈50岁组,FF%与VAT或SAT均无明显相关性（r分别为-0.076、-0.067,P〉0.05）。结论中老年女性（≥50岁）腰椎骨髓脂肪含量与VAT关系密切,男性与年轻女性（〈50岁女性）腰椎骨髓脂肪含量与腹部脂肪无关。Objective To investigate the correlation between the lumbar bone marrow fat and abdominal fat. Methods A total of68 individuals（32 men and 36 women, aged 21- 74 years with a median of 49.5 years） were included in this study. All the subjects underwent spectroscopic examination of the third lumber vertebra with the single voxel method on a 1.5T MR scanner to measure the fat fraction（FF%）. Quantitative CT was also performed for measurement of the abdomen subcutaneous adipose tissue（SAT） and visceral adipose tissue（VAT）. The measurements were compared between subjects aged ≥50 years and those below 50 years, respectively,in male or female subjects. Results In male subjects, BMI, FF%, VAT or SAT showed no significant differences between the two age groups（P〈0.05）, and FF% was not correlated with BMI, VAT or SAT（r=0.109, 0.034, 0.066,respectively; P〈0.05）. In the female subjects, BMI, FF%, VAT and SAT differed significantly between the two age groups（P〈0.05）, and in ≥50 years group, FF% showed a positive correlation with VAT（r=0.499, P〈0.05） but was not correlated with SAT（r=0.221, P〈0.05）; in50 years group, FF% was not correlated with VAT or SAT（r=0.076,- 0.067, respectively; P〈0.05）.Conclusion FF% is positively correlated with VAT in female subjects aged beyond 50 years, but is not correlated with VAT or SAT in male subjects or in younger female subjects.

关 键 词：骨髓脂肪 磁共振波谱 内脏脂肪 定量CT 

分 类 号：R580[医药卫生—内分泌]