循证护理用于自体DC/CIK细胞维持治疗晚期肺腺癌护理中的效果分析  

Analysis of the effects of evidence-based nursing applied in the nursing of autologous DC/CIK cells maintenance in the treatment of advanced pulmonary adenocarcinoma

作　　者：沈小丽[1] 邱国琴[1] 陆华东[1] 王斌[1] 

机构地区：[1]浙江大学湖州医院呼吸内科浙江省湖州市呼吸病研究所,浙江湖州313000

出　　处：《中国现代医生》2016年第6期122-125,共4页China Modern Doctor

基　　金：浙江省医药卫生平台计划项目(学科带头人)(2015DTA016)

摘　　要：目的对循证护理方式用于自体DC/CIK细胞维持治疗晚期肺腺癌护理中的效果进行分析,为循证护理推广和晚期癌症生存质量的改善提供指导。方法选取我院呼吸内科、胸外科及肿瘤科2013年6月~2015年4月间采用自体DC/CIK细胞维持治疗的晚期肺腺癌患者85例为研究对象,采用随机数字表法分为观察组和对照组,并分别予以循证护理和常规护理两种方式予以护理。治疗后就其疗效、不良反应、生存质量及护理满意率等进行评价及组间比较。结果观察组总有效率为65.12%,对照组总有效率为57.15%,两组比较差异无统计学意义（P〉0.05）;两组研究对象的不良反应发生率分别为27.91%和38.10%,观察组显著低于对照组（P〈0.05）,即观察组的安全性显著高于对照组;治疗后观察组生活质量问卷平均分为（64.8±7.4）分,生活质量优良率88.37%,总护理满意率为93.02%,均显著优于对照组（P〈0.05）。结论循证护理方式用于自体DC/CIK细胞维持治疗晚期肺腺癌护理中能够提高其安全性,改善生存质量,提升护理满意率,具有良好的临床效果。Objective To analyze the effects of evidence-based nursing applied in the nursing of autologous DC/CIK cells maintenance in the treatment of advanced pulmonary adenocarcinoma, so as to provide guidance for the promotion of evidence-based nursing and the improvement of life quality for advanced cancer. Methods A total of 85 patients with advanced pulmonary adenocarcinoma who were given the treatment of autologous DC/CIK cells maintenance in the Department of respiratory medicine, the department of thoracic surgery and the department of oncology in our hospital from June 2013 to April 2015 were selected as research subjects. They were assigned to the observation group and the control group accoroling to the method of random number table, and were given two ways of nursing, evidence-based nursing and regular nursing. After the treatment, the data such as curative effects, adverse effects, life quality and nursing satisfaction rate were evaluated and compared between groups. Results The total effective rate was 65.12% in the observation group and 57.15% in the control group, there was no significant difference between the two groups（P〉0.05）;the incidence rate of adverse effects in the two groups of subjects was 27.91% and 38.10% respectively, the observation group was significantly lower than the control group（P〈0.05）. The safety in the observation group was significantly higher than that in the control group; after the treatment, the average score of life quality questionnaire in the observation group was（64.8±7.4）, the good rate of life quality was 88.37%, and the total nursing satisfaction rate was 93.02%, which were all significantly better than those in the control group（P〈0.05）. Conclusion Evidence-based nursing applied in the nursing of autologous DC/CIK cells maintenance in the treatment of advanced pulmonary adenocarcinoma is able to improve its safety, enhance life quality, and increase the nursing satisfaction rate, which is of favorable clinical effects.

关 键 词：循证护理 自体DC/CIK细胞维持 晚期肺腺癌 生存质量 不良反应 

分 类 号：R473.7[医药卫生—护理学]