去除白细胞的血液输注对膀胱癌患者免疫性输血反应的影响研究  

Effect of Blood Transfusion on the Immune Response of Patients With Bladder Cancer

作　　者：石洁[1] 杨勇毅[2] 高琲[3] 李晓娟[1] 杨兰[1] 

机构地区：[1]甘肃兰州大学第二医院输血科,730030 [2]甘肃省血液中心,兰州730046 [3]甘肃省人民医院药剂科,兰州730000

出　　处：《中国卫生标准管理》2016年第3期182-183,共2页China Health Standard Management

基　　金：甘肃省科技厅青年基金(项目编号:145RJYA252)

摘　　要：目的探讨去除白细胞血液输注对膀胱癌患者预防免疫性输血反应的作用。方法抽取7 d、14 d保存期红细胞悬液60个U(单位/袋),分别对观察组与对照组不同的血液输注,比较两组患者输血反应发生率。结果保存期7 d、14 d过滤白细胞前、后患者的钠离子、p H值、Hb浓度等指标差异无统计学意义,观察组和对照组输血反应发生率组间比较差异具有统计学意义(P<0.05)。结论白细胞过滤能有效去除血液中白细胞,在一定程度上降低免疫性发热输血反应发生率。Objective To investigate the removal of white blood cells in the blood infusion of bladder cancer patients to prevent immune transfusion reaction. Methods The extraction of 7 d,14 d shelf life of red blood cell suspension 60 U（units/bag）,respectively,for the observation group and the control group,the different blood infusion,compared two groups of patients with blood transfusion reaction rate. Results The preservation period of 7 d,14 d filtered white cells before and after the sodium ion,p H value,Hb concentration index,there was no statistically significant difference in the observation group and the control group blood transfusion reaction rate between group difference was significant（P〈0.05）. Conclusion White cell filtering can effectively remove blood white cells in a certain degree.

关 键 词：去除白细胞血液输注 膀胱癌 免疫性输血反应 

分 类 号：R331[医药卫生—人体生理学]