地佐辛与曲马多用于老年肱骨内固定手术术后镇痛的临床效果比较  

The clinical effect of dezocine and tramadol for proximal humerus internal fixation surgery postoperative analgesia

作　　者：张碧欣[1] 杨帅[1] 何斌[1] 华丽[1] 

机构地区：[1]成都大学附属医院麻醉科,成都市610000

出　　处：《临床合理用药杂志》2016年第8期9-10,共2页Chinese Journal of Clinical Rational Drug Use

摘　　要：目的探讨地佐辛与曲马多用于老年患者肱骨内固定手术术后镇痛的效果。方法选取2013年9月-2015年1月于医院行全身麻醉下肱骨内固定手术的老年患者70例,随机分为地佐辛组(D组)和曲马多组(Q组)各35例。D组术后采用地佐辛+舒芬太尼+昂丹司琼镇痛;Q组术后采用曲马多+舒芬太尼+昂丹司琼镇痛。观察2组患者术后镇痛评分(VAS)、镇静评分(Ramsay)及不良反应发生情况。结果 D组在术后0.5h、3h的VAS评分均低于Q组,差异有统计学意义(P<0.05),D组Ramsay评分在3h时优于Q组,差异有统计学意义(P<0.05),D组发生不良反应的例数也少于Q组,差异有统计学意义(P<0.05)。结论地佐辛较曲马多的镇痛镇静效果确切,且不良反应少于曲马多组,可安全用于老年患者肱骨内固定术后镇痛。Objective To investigate theclinical effect of dezocine and tramadol for proximal humerus internal fixation surgery postoperative analgesia. Methods 70 cases of elderly patients with humerus internal fixation surgery,were randomly divided into dezocine group（ D group） and tramadol group（ Q group）,35 cases in each. All patients underwent general anesthesia. D group of postoperative analgesia with dezocine ＋ sufentanil ＋ ondansetron; Q group of postoperative analgesia with tramadol ＋ sufentanil ＋ ondansetron. To observe the postoperative pain score（ VAS）,sedation score（ Ramsay） and adverse reactions. Results VAS scores of group D in 0. 5 h,3 h were lower than that of group Q,with statistical significance（ P 0. 05）. Ramsay scoreof group D in 3 his better than that of group Q,withstatistically significance（ P 0. 05）. In group D,adverse reactions were also less,with statistically significancy（ P 0. 05）. Conclusion The sedative effect of dezocine analgesiais more effective,and the side effects were significantly less,which proved it is safer for elderly patientsunder internal fixation of proximal humeral.

关 键 词：地佐辛 曲马多 肱骨内固定术 老年 术后镇痛 

分 类 号：R614[医药卫生—麻醉学]