阻塞性呼吸睡眠暂停综合征与高血压的研究进展  

Progress in research on obstructive sleep apnea syndrome with hypertension

作　　者：李洁[1] 谢晶[1] 姜懋 黄娟娟[1] 杨天伦[2] 

机构地区：[1]中南大学湘雅医学院,长沙410013 [2]中南大学湘雅医院心内科,长沙410008

出　　处：《中南大学学报（医学版）》2016年第2期212-217,共6页Journal of Central South University ：Medical Science

基　　金：国家自然科学基金(81370320,81241009,81570334)~~

摘　　要：阻塞性睡眠呼吸暂停综合征(obstructive sleep apnea syndrome,OSAS)是一种常见但易被忽视的疾病,是由于某些原因引起上呼吸道阻塞而出现睡眠呼吸暂停并伴有缺氧、鼾声、白天嗜睡等症状的慢性睡眠呼吸障碍性疾病。OSAS与高血压密切相关,可能通过多种机制引起高血压的发生。OSAS的诊断主要依据患者的病史、体征及多导睡眠图监测结果,如睡眠呼吸暂停和低通气次数。主要可通过持续气道内正压通气、口腔矫正、药物及改变生活方式等进行改善与治疗。Obstructive sleep apnea syndrome（OSAS） is a complicated chronic disease caused by certain reasons, characterized by obstruction of the upper airway and apnea or hypopnea during sleep,which can be followed by anoxia, snoring and daytime sleepiness. Recent studies have shown that hypertension is closely connected to OSAS. OSAS can lead to hypertension by several possible mechanisms. The diagnosis of OSAS mainly depends on the medical history, sign, polysomnogram（PSG） result and the frequency of apnea and hypopnea. OSAS can be relieved by continuous positive airway pressure（CPAP）, oral orthodontic treatment, medicine, change of lifestyles and others. Th is brief review focuses on the mechanism of hypertension due to OSAS and the diagnosis criteria and treatment of OSAS.

关 键 词：阻塞性呼吸睡眠暂停综合征 高血压 发病机制 诊断标准 处理方法 

分 类 号：R766[医药卫生—耳鼻咽喉科] R544.1[医药卫生—临床医学]