梅毒血清学检测在诊断咽喉部病变患者的临床意义  

Clinical significance of syphilis serological detection in the diagnosis of patients with pharynx and larynx diseases

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作  者:周冰[1] 陆奎英[1] 刘文娟[1] 王静玉[1] 张江云[2] 

机构地区:[1]江苏省扬州市第一人民医院检验科,扬州225001 [2]江苏省扬州市第一人民医院耳鼻喉科,扬州225001

出  处:《中国眼耳鼻喉科杂志》2016年第2期120-121,共2页Chinese Journal of Ophthalmology and Otorhinolaryngology

摘  要:目的分析梅毒血清学检测在诊治咽喉部病变患者的临床意义,以减少误诊、漏诊的发生。方法采用化学发光微粒子免疫分析技术(CMIA)进行梅毒螺旋体(TP)抗体检测,阳性标本进行甲苯胺红不加热血清试验(TRUST)。结果咽喉科6 027例研究对象中,TP抗体阳性者206例。在206例TP抗体阳性病例中,TRUST滴度≥1∶8的29例,其中有5例以咽喉痛为主诉,首诊误诊为化脓性扁桃体炎、咽峡炎,最终确诊为咽喉部梅毒。结论很多性器官外梅毒患者常首诊于咽喉科,极易误诊、漏诊,以咽痛为主诉,咽喉部黏膜有灰白色假膜的患者,均建议进行TP-CMIA和TRUST检测。Objective To analyze the clinical significance of serological detection of syphilis in the diagnosis of patients with pharynx and larynx diseases in order to reduce the incidence of misdiagnosis and missed diagnosis. Methods Chemiluminescent microparticle immunoassay( CMIA) was used to detect the treponema pallidum( TP) antibody,and the positive samples were detected by tolulized red unheated serum test( TRUST). Results There were 206 cases of anti-TP positive in 6 027 cases with pharynx and larynx diseases,and the TRUST titre in 29 cases was ≥1∶ 8,in which 5 cases was with throat pain complaint and was misdiagnosed for suppurative tonsillitis,pharyngitis. Conclusions Many non-genitals syphilis patients are usually first diagnosed in the throat department who are easy to be misdiagnosed and missed diagnosed.Patients with the chief complaint of sore throat,throat mucosa with gray white pseudomembrane should be tested with TPCMIA and TRUST.

关 键 词:咽喉科 梅毒血清学试验 咽喉部梅毒 误诊 漏诊 

分 类 号:R76[医药卫生—耳鼻咽喉科]

 

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