动态血糖监测系统联合胰岛素泵治疗新诊断2型糖尿病患者的疗效观察  

Clinical observation of insulin pump combined with continuous glucose monitoring system in newly diagnosed type 2 diabetic patients

作　　者：李晓蕾[1] 齐晓玲[1] 徐礼五[1] 段成[1] 胡文文[1] 

机构地区：[1]安徽省淮南市第一人民医院内分泌科,232001

出　　处：《中国糖尿病杂志》2016年第3期219-222,共4页Chinese Journal of Diabetes

摘　　要：目的观察新诊断T2DM患者采用动态血糖监测系统(CGMS)联合胰岛素泵治疗对血糖控制的效果。方法将80例新诊断T2DM患者分为研究组41例,采用CGMS联合胰岛素泵治疗;对照组39例,采用胰岛素皮下注射结合指尖血糖监测治疗。结果研究组FPG、2 hPG和C—RP低于对照组,胰岛β细胞功能指数(HOMA—β)高于对照组(P<0.05)。研究组血糖达标时间[(6.3±1.5)vs(9.6±1.8)d]、低血糖发生次数[(10.5±3.8)vs(28.6±5.8)次]、胰岛素用量[(38±4)vs(43±4)U/d]、血糖波动值[(3.17±1.53)vs(5.24±1.79)mmol/L]均低于对照组(P<0.01)。结论采用CGMS联合胰岛素泵治疗新诊断T2DM患者,有利于进一步精细的调控胰岛素用量,尽快达到降血糖的目的,降糖效果更平稳。Objective To observe the clinical effect of insulin pump therapy combined with continuous glucose monitoring system（CGMS） in newly diagnosed type 2 diabetes（T2DM）.Methods80 cases of newly diagnosed T2 DM were divided into treatment group（n = 41,insulin pump therapy combined with CGMS） and control group（n = 39,routine subcutaneous insulin injection therapy combined with fingertip blood glucose monitoring）.Results The levels of FPG,2 hPG,and C-RP after treatment were significantly lower in treatment group than in control group,and HOMA-β index was significantly higher in treatment group than in control group（P〈0.05）.Time of blood glucose reaching target[（6.3± 1.5） vs（9.6±1.8） d],the incidence of hypoglycemia[（10.5 ± 3.8） vs（28.6 ± 5.8） times],insulin dosage[（38±4） vs（43 ± 4） U/d],blood glucose fluctuation value[（3.17±1.53） vs（5.24 ± 1.79）mmol/L]were significantly lower in treatment group than those in control group（P〈0.05）.Conclusion Insulin pump therapy combined with CGMS is conducive to finely regulate insulin dose and achieve smooth glucose control as soon as possible.

关 键 词：新诊断 糖尿病 2型 动态血糖监测系统 胰岛素泵 血糖控制 

分 类 号：R587.1[医药卫生—内分泌]