The role of the unfolded protein response in myelination  被引量:1

The role of the unfolded protein response in myelination

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作  者:Michelle C.Naughton Jill M.McMahon Una F.FitzGerald 

机构地区:[1]NCBES,Galway Neuroscience Centre,National University of Ireland Galway

出  处:《Neural Regeneration Research》2016年第3期394-395,共2页中国神经再生研究(英文版)

摘  要:The production,transport and integration of myelin components into the membrane during development is a highly coordinated and regulated process that relies heavily on the endoplasmic reticulum(ER),a sub-cellular organelle that is the principal site of membrane assembly.Ribosomes on the rough ER allow translation of proteins such as proteolipid protein(PLP)prior to correct folding,The production,transport and integration of myelin components into the membrane during development is a highly coordinated and regulated process that relies heavily on the endoplasmic reticulum(ER),a sub-cellular organelle that is the principal site of membrane assembly.Ribosomes on the rough ER allow translation of proteins such as proteolipid protein(PLP)prior to correct folding,

关 键 词:endoplasmic translational reticulum prior folding assembly coordinated myelin correct tracts 

分 类 号:R338[医药卫生—人体生理学]

 

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