Tei指数评价吸烟人群中糖尿病患者左心功能  

Evaluation of left ventricular function of smokers with diabetes by Tei index

作　　者：梁丽萍[1] 任海波[1] 郑艳芬[1] 

机构地区：[1]包头医学院第二附属医院,内蒙古包头014030

出　　处：《中国民康医学》2016年第5期4-6,9,共4页Medical Journal of Chinese People’s Health

基　　金：包头医药卫生基金资助(编号2012 S 2006-02-07)

摘　　要：目的:探讨用Tei指数评价吸烟人群中糖尿病患者左心功能的临床价值。方法:将120例2型糖尿病患者按是否吸烟分为糖尿病吸烟组和糖尿病组,每组各60例。将120例健康体检者按是否吸烟分为单纯吸烟组和对照组,每组各60例。各组研究对象均行超声心动图检查,获取左室射血分数(LVEF)、左室短轴缩短率(LVFS)值、二尖瓣瓣尖处舒张期E波峰速度(E)、A波峰速度(A)、计算E/A比值。Tei软件测量二尖瓣血流频谱A峰至下一E峰间距(a),主动脉血流频谱射血间期(b),a-b/b即为左室Tei指数,并进行比较。结果:糖尿病吸烟组、糖尿病组、单纯吸烟组研究对象间LVEF、LVFS无显著差异(P>0.05)、左心室Tei指数均明显高于对照组(P<0.05);糖尿病吸烟组患者的左室E、E/A低于对照组(P<0.05);糖尿病吸烟组患者的左心Tei指数较糖尿病组及单纯吸烟组明显增高(P<0.05)。结论:Tei指数较LVEF、LVFS、E/A更准确、全面地估测左心室收缩与舒张功能,吸烟可加重糖尿病患者左心室整体功能的损害。Objective To discuss clinical value of evaluation of left ventricular function of smokers with diabetes by Tei index.Methods： According to smoking or not, 120 patients with type 2 diabetes were divided into diabetes ＋ smoking group （60 cases） anddiabetes group （60 cases）. 120 healthy test people were also classified as pure smoking group （60 cases） and control group （60 cases）. All the testers undergone echocardiography to acquire left ventricular ejection fraction （LVEF） and left ventricular fractionalshortening （LVFS）; and the pulse Doppler wave measured peak value flow velocity of early diastolic period （peak E）, peak value flowvelocity of late diastolic period （peak A）, and the ratio of peak E to peak A （E/ A） was calculated. Further, the Tei software wasused to measure the a value （isovolumetric contraction time add isovolumetric relaxation time add ejection time） and b value （ejectiontime）, and then the Tei index （a-b/b） was calculated. Results： Compared with diabetes ＋ smoking groups, diabetes groups, puresmoking groups, there were no significant differences in LVEF and LVFS （P〉0. 05）; however, the Tei index was significantly higherthan that of control group （P〈0. 05）. The peak E and E/ A of diabetes ＋ smoking group were lower than those of control group （P〈0. 05）, but the Tei index was significantly higher than those of diabetes group and pure smoking group （P〈0. 05）. Conclusions： TheTei index is more accurate and comprehensive than LVEF, LVFS, E/ A in evaluating left ventricular systolic and diastolic functionchanges, and smoking could further increase left ventricular function damage of the diabetes mellitus patients.

关 键 词：超声心动图 TEI指数 糖尿病 吸烟 心功能 

分 类 号：R587.1[医药卫生—内分泌]