1例鲍曼不动杆菌肺部感染患者的药学监护  

Pharmaceutical care on a patient with pulmonary infection by Acinetobacter baumannii

作　　者：张红梅[1] 郭秋实[1] 孙丽蕊[1] 田旭[1] 孙智辉[1] 

机构地区：[1]吉林大学第一医院二部药学部,吉林长春130031

出　　处：《中国药物应用与监测》2016年第2期92-94,共3页Chinese Journal of Drug Application and Monitoring

摘　　要：1例66岁老年男性患者,因车祸入院,术后出现肺部感染,多次痰培养为泛耐药鲍曼不动杆菌,临床药师评估抗感染治疗方案,建议将抗感染药物调整为米诺环素胶囊与头孢哌酮舒巴坦联合用药,患者症状好转。入院第2天,患者出现头痛、心悸,考虑为单硝酸异山梨酯的不良反应,停用该药后患者头痛、心悸症状消失。入院第16天患者出现抗生素相关性腹泻,给予停用抗感染药物、调节肠道菌群治疗后好转。在治疗过程中,药师协助医师及时评估抗感染方案,在抗感染药物的调整、不良反应原因解析等方面进行全程药学监护。经对症治疗后,患者病情好转出院。One 66-year-old male patient was admitted to hospital due to a traffic accident. After surgery, the patient gotextensively drug resistant Acinetobacter baumannii pulmonary infection. Clinical pharmacists evaluated the anti-infective treatmentprograms, adjusted anti-infective drugs to minocycline capsules and cefoperazone sulbactam, which improved the symptoms ofpatient. After 2-day treatment, the patient got headache and palpitations, the symptoms disappeared after drug withdrawal, so thesymptoms were considered as adverse drug reactions of isosorbide mononitrate. The patient had antibiotic-associated diarrhea onthe 16th day, and improved after anti-infective drugs withdrawal and regulation of intestinal flora during the treatment. Pharmacistsassisted the physicians in the assessment of anti-infective treatment, took pharmaceutical cares on adjusting anti-infective drugs andanalyzing the reasons of ADR. After symptomatic treatment, the patient was discharged with an improved condition.

关 键 词：临床药师 鲍曼不动杆菌 肺部感染 药学监护 

分 类 号：R563.1[医药卫生—呼吸系统]