抗HIV抗体ELISA S/CO比值与确证试验阳性结果的相关性分析  

Study on the Correlation of the Anti-HIV ELISA S/CO Ratio and the Positive Result of Confirmatory Test

作　　者：赵鲁强[1] 

机构地区：[1]贵州医科大学附属医院输血科,贵州贵阳550001

出　　处：《沈阳医学院学报》2016年第2期78-79,共2页Journal of Shenyang Medical College

摘　　要：目的:探讨抗人类免疫缺陷病毒(HIV)酶联免疫吸附试验(ELISA)S/CO比值与确证试验阳性结果的相关性。方法:采用某国产ELISA试剂筛查82 506例我院门诊及住院患者血液标本,初筛结果阳性标本用免疫印迹试验法进行确证,并进行相关性分析。结果:82 506例标本中经抗HIV ELISA试剂初筛阳性375例,经免疫印迹试验确证阳性333例,总阳性率88.9%;S/CO≥10.0确证结果阳性率明显高于S/CO<10.0,差异有统计学意义(P<0.01)。结论:抗HIV ELISA S/CO比值与免疫印迹试验确证试验阳性结果有一定的相关性,S/CO比值可以在一定程度上预测抗HIV阳性。Objective： To investigate the anti-HIV ELISA S/CO ratio and the positive result of the Western blot confirmatory test.Methods： A total of 82 506 outpatients and hospitalized patients in our hospital were screened with some domestically diagnostic kits.Positive results were confirmed with Western blot test. Correlation analysis was carried on. Results： In 82 506 cases,375 were anti-HIV positive,of which 333 positive cases were detected by Western blot confirmatory test. Total positive rate was 88. 9%. Positive rate in S / CO≥10. 0 cases detected by the domestically diagnostic kits was apparently higher than that in S/CO〈10. 0 cases,the difference was statistically significant（ P〈0. 01）. Conclusion： The anti-HIV ELISA S / CO ratio is correlated with confirmatory test,so S/CO ratio can be used to predict anti-HIV positive.

关 键 词：抗HIV S/CO比值 ELISA 免疫印迹试验 

分 类 号：R446.62[医药卫生—诊断学]