肺癌患者化疗后应用甲地孕酮致深静脉血栓治疗的分析与探讨  

Analysis and discussion on deep vein thrombosis induced by megestrol acetate dispersible tablets in a lung cancer patient

作　　者：钱春艳[1] 蔡小军[2] 宋惠珠[2] 陆守荣[2] 

机构地区：[1]常州市第一人民医院药学部,江苏常州213003 [2]南京医科大学附属无锡市人民医院药学部,江苏无锡214023

出　　处：《中国医院药学杂志》2016年第5期404-406,共3页Chinese Journal of Hospital Pharmacy

摘　　要：1例38岁女性患者,因肺腺癌晚期食欲欠佳及恶液质状态,口服甲地孕酮分散片(宜利治)160 mg·d-1治疗。1周后,患者出现左下肢深静脉血栓,停药并启动低分子肝素、华法林抗凝治疗。14 d后,患者患肢肿胀、疼痛减轻,下肢深静脉血管部分再通,予出院后口服华法林3.75 mg·d-1继续抗凝治疗并定期监测PT-INR。A 38 years old female patient with advanced lung adenocarcinoma,with anorexia and dyscrasia,was treated with megestrol dispersible tablets at 160 mg·d^- 1. After 1 week,left lower extremity had deep vein thrombosis. Former drug was withdrawn,low molecular heparin and warfarin were administered. After 14 days,limb swelling and pain were alleviated and involved deep vein was partly reopened. After the patient was discharged,warfarin was administered at 3. 75 mg / d continuously,PT and INR were regularly monitored.

关 键 词：甲地孕酮分散片 深静脉血栓 华法林 

分 类 号：R979.1[医药卫生—药品]