老年高血压患者动态动脉硬化指数与脉搏波传导速度、脉压指数的相关性  

Correlation between AASI and ba PWV, PPI in Elderly Patients with Essential Hypertension

作　　者：孙艳[1] 杨苏[1] 何燕[1] 杨莉[1] 杨文慧[1] 刘师节 甘露路 董阳[1] 

机构地区：[1]昆明医科大学附属延安医院老年病科,云南昆明650051

出　　处：《昆明医科大学学报》2016年第2期93-95,共3页Journal of Kunming Medical University

基　　金：云南省科技厅-昆明医科大学应用基础研究联合专项基金资助项目(2012FB098;2013FZ286)

摘　　要：目的分析老年原发性高血压患者动态动脉硬化指数(AASI)与脉搏波传导速度(ba PWV)、脉压指数(PPI)的关系,探讨这些指标在老年高血压患者动脉弹性评估中的意义.方法选择昆明医科大学附属延安医院2014年5月至2015年2月门诊及住院治疗的老年原发性高血压患者89例,分别进行动态血压检测和无创动脉硬化检测,采用Spearman分析AASI与ba PWV、PPI的相关性.结果本组89例研究对象中ba PWV为(1 603.41±19.84)cm/s,AASI为(0.61±0.15),PPI为(0.44±0.06).Spearman等级相关分析显示,AASI与平均舒张压呈负相关(r=-0.157,P<O.05).ba PWV、PPI、平均脉压、平均收缩压与AASI呈正相关(r=0.685、0.701、0.648、0.416,P<O.01),且AASI与Ba PWV、PPI的相关系数最高.结论AASI可以反映动脉硬化的程度,随着AASI数值的增大,ba PWV、PPI也随之增大.Objective To investigate the relationship between the level of AASI and ba PWV, PPI and explore the meaning of these indexes for arteriosclerosis assessment in elderly hypertensive patients. Methods Eighty- nine elderly essential hypertension patients who were outpatients and inpatients in our hospital were included in this study from May 2014 to February 2015. Ambulatory blood pressure monitoring and noninvasive arteriosclerosis detection were measured and the relationship between AASI and ba PWV, PPI was also analyzed. Results The level of ba PWV of 89 patients was（ 1603.41 ±19.84） cm/s, AASI was（ 0.61 ±0.15）, and PPI was（ 0.44 ±0.06）. Spearman correlation analysis showed that AASI was negatively correlated with the average diastolic blood pressure（ r = 0.157, P〈0.05）. Ba PWV, PPI, mean arterial blood pressure and mean systolic blood pressure was positively correlated with AASI（ r = 0.685, 0.701, 0.648, 0.701, P〈0.01）. AASI, ba PWV and PPI had higher correlation coefficient.Conclusion AASI can reflect the extent of atherosclerosis, and Ba PWV and PPI may increase with the increase of AASI.

关 键 词：高血压 动脉硬化 脉搏波传导速度 

分 类 号：R544.1[医药卫生—心血管疾病]