昆明地区慢性阻塞性肺疾病患者肺功能影响因素分析  

The Analysis of Influential Factors of Pulmonary Function in Patients with Chronic Obstructive Pulmonary Disease in Kunming

作　　者：毕虹[1] 金志贤[1] 陈敏[1] 杜俊毅[1] 

机构地区：[1]昆明市第一人民医院呼吸二科,云南昆明650011

出　　处：《昆明医科大学学报》2016年第1期115-118,共4页Journal of Kunming Medical University

基　　金：昆明市科技局基金资助项目(昆科技字2014-04-A-S-02-3119)

摘　　要：目的探讨昆明地区慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)患者肺功能影响因素.方法选取昆明地区5家三甲医院确诊为COPD的住院患者共300例为研究对象,通过自行设计的调查表对研究对象进行问卷调查,分析COPD患者肺功能影响因素.结果采用两变量间直线相关分析发现:COPD患者文化程度、经济收入、戒烟年数与第1秒用力呼气容积占预计值(percentage of the forced expiratory volume in one second divided by the predicted value,FEV1%pre)正相关性(r值分别为0.318、0.309、0.113,P值分别为0.000、0.000、0.05),吸烟指数、烟草依赖评分与FEV1%pre负相关(r值分别为-0.202、-0.323,P值分别为0.000、0.000).经多重线形回归分析显示:FEV1%pre=34.792-1.765×烟草依赖评分+2.558×文化程度+2.587×经济收入,在性别、年龄、体块指数、文化程度、经济收入、吸烟指数、是否戒烟、戒烟年数、烟草依赖评分9个因素中,烟草依赖评分是影响FEV1%pre的主要因素.结论 COPD患者文化程度、经济收入越高,戒烟年数越久,吸烟指数与烟草依赖评分越低,患者FEV1%pre越高.烟草依赖评分是影响COPD患者FEV1%pre的主要因素.Objective To explore the influential factors of pulmonary function in patients with chronic obstructive pulmonary disease（COPD） in Kunming district. Methods A total of 300 patients with COPD were selected from 5 tertiary hospitals in Kunming district as subjects investigated. The subjects were investigated by self-designed questionnaire,and then the influential factors of patients with COPD were analyzed. Results By linear correlation analysis, there were positive correlation between each of degree of education, economic income, the number of quitting smoking and percentage of the forced expiratory volume in one second divided by the predicted value（ FEV1% pre）（ r values respectively were 0.318, 0.309, 0.113, P values respectively were0.000, 0.000, 0.05）, there were negative correlation between smoking index, tobacco dependence score and FEV1%pre（r values respectively were-0.202,-0.323, P values respectively were 0.000,0.000）. By multiple linear regression analysis,FEV1%pre=34.792-1.765×tobacco dependence score＋2.558×degree of education＋2.587×economic income, in the nine influential factors（gender,age,body mass index, degree of education,economic income,smoking index,whether to give up smoking,number of quitting smoking, tobacco dependence score）, the tobacco dependence score was the main factor affecting FEV1% pre. Conclusions The higher the degree of education,economic income of the patients with COPD have,the longer number of years of the patients with COPD quit smoking,the lower smoking index and tobacco dependence score tobacco dependence score have,the higher the FEV1%pre of the patients with COPD have. The tobacco dependence score is the main factor affecting FEV1%pre.

关 键 词：昆明地区 慢性阻塞性肺疾病 肺功能 影响因素 

分 类 号：R563[医药卫生—呼吸系统]