TEMPO抑制K_2S_2O_8氧化甲苯生成苯甲醛过程中的过度氧化  

TEMPOs Suppressing Overoxidation in K_2S_2O_8 Oxidation of Toluene to Benzaldehyde

作　　者：林淑英[1] 金旭康 刘仁华[1] 

机构地区：[1]华东理工大学药学院,上海200237

出　　处：《化学试剂》2016年第4期357-360,共4页Chemical Reagents

基　　金：国家自然科学基金资助项目(21072055)

摘　　要：采用TEMPO/Cu(OAc)2为催化剂,探究其在抑制苯甲醛过度氧化成苯甲酸方面的能力,考察反应时间、反应温度、催化剂用量等因素对苯甲醛收率的影响。研究结果表明,TEMPO以及TEMPO衍生物在Cu(OAc)2催化下,可以有效地抑制甲苯合成苯甲醛过程中苯甲醛进一步氧化成苯甲酸。优化条件下,甲苯氧化生成苯甲醛的收率高达78%,而且没有苯甲醇和苯甲酸生成。The capability of inhibiting the overoxidation of benzaldehyde by using TEMPO / Cu（ OAc）2as the catalyst was investigated. The effects of operation parameters,such as reaction time,reaction temperature were investigated. The experimental results showed that the formation of benzoic acid from aldehyde products overoxidation can be inhibited by the addition of TEMPO and TEMPO derivatives in Cu（ OAc）2as the catalysts. Under the optimum condition,the yield of benzaldehyde from toluene was up to78%,while no benzyl alcohol and benzoic acid was formed.

关 键 词：甲苯氧化 苯甲醛 Cu(OAc)2/TEMPO K2S2O8 

分 类 号：O626.2[理学—有机化学]