果胶负载钯催化剂的制备及Suzuki反应催化性能  

Preparation and Suzuki Reaction Performance of Pectin-supported Palladium Catalyst

作　　者：周文俊[1] 周宇[1] 张霞忠[1] 曾彬[1] 

机构地区：[1]内江师范学院化学化工学院,内江641112

出　　处：《高等学校化学学报》2016年第4期669-673,共5页Chemical Journal of Chinese Universities

基　　金：四川省教育厅重大成果转化项目(批准号:12ZZ012);四川省教育厅自然科学青年基金项目(批准号:12ZB074;13ZB0002);内江师范学院博士科研启动费项目(批准号:2012B05)资助~~

摘　　要：以柑橘皮果胶为载体,采用吸附法制备了果胶负载钯催化剂,并将其应用于四苯硼钠与溴代芳烃的交叉偶联反应中.该反应体系以聚乙二醇400（PEG 400）/H2O为反应溶剂,三乙胺为碱,在空气中于110℃反应15～60 min,四苯硼钠中4个苯基均可顺利参与反应,高产率地获得相应的目标化合物.该方法具有条件温和、反应时间短、收率高且催化剂可循环利用等优点.To discover new heterogeneous palladium catalyst in organic synthesis,pectin,which was extracted form citrus peel,was used as supporter for the preparation of pectin-supported palladium catalyst. The pectinsupported palladium catalyst was applied to Suzuki cross-coupling reaction between sodium tetraphenylborate and aryl bromides. The results revealed that all four aryl groups of sodium tetraryylborate could be efficiently utilized in the Suzuki cross-coupling reactions in an atom-efficient way in the presence of Et3 N as base in PEG 400 / H2 O at 110 ℃ in open air,providing excellent yields of the corresponding functionalized biaryls within 1 h. The present protocol has the advantages highly efficient,high yield,mild condition,short reaction time,as well as the catalyst can be recycled and reused.

关 键 词：果胶负载钯 SUZUKI反应 四苯硼钠 溴代芳烃 

分 类 号：O621.25[理学—有机化学]