氧化锆陶瓷与镍铬合金口腔材料的细菌黏附性对比  

Bacterial adhesion of zirconia ceramics versus nickel chromium alloy as oral materials

作　　者：韩月红[1] 成之远 王明德[3] 

机构地区：[1]临朐县人民医院,山东省潍坊市262600 [2]临胸县中医院,山东省潍坊市262600 [3]潍坊市人民医院,山东省潍坊市261041

出　　处：《中国组织工程研究》2016年第8期1089-1094,共6页Chinese Journal of Tissue Engineering Research

摘　　要：背景:实验及临床经验表明,修复材料表面的粗糙度直接影响细菌的黏附性,除此之外,材料组成及本身理化性质也是重要影响因素。目的:对比氧化锆陶瓷与镍铬合金口腔材料的细菌黏附性。方法:将氧化锆陶瓷、镍铬合金分别制成3.0 cm×3.0 cm×0.2 cm的板片,每种材料各10片。两种材料各选取其中5片进行抛光处理,另5片进行上釉处理,检测4组试件的粗糙度。将变形链球菌浮液滴加于4组材料表面,37℃厌氧培养48 h,检测各组细菌黏附数量。结果与结论:4组试件表面粗糙度比较差异无显著性意义。氧化锆陶瓷抛光组的细菌黏附量明显小于镍铬合金抛光组(P<0.05),氧化锆陶瓷上釉组的细菌黏附量与镍铬合金上釉组比较差异无显著性意义。结果表明氧化锆陶瓷具有较好抑制细菌黏附的效果,其上釉处理后抑制细菌黏附的效果与镍铬合金上釉处理后的相当。BACKGROUND： Experimental and clinical experiences show that the surface roughness of dental restoration materials directly affects bacterial adhesion; in addition, the material composition and physicochemical properties are also important influencing factors. OBJECTIVE： To compare the bacterial adhesion of zirconia ceramics and nickel chromium alloy as oral materials. METHODS： Zirconia ceramics and nickel chromium alloy were respectively cut into 10 pieces of 3. 0 cm ×3.0 cm×0. 2 cm plate specimens. For each material, five pieces were subjected to surface polishing treatment, and the other five pieces were glazed. Surface roughness value of specimens was detected. Experimental strains of Streptococcus mutans was cultured on the specimen surface at 37 ℃ for 48 hours, and the amount of bacteria adhering to the specimen surface was detected. RESULTS AND CONCLUSION： Surface roughness of four groups of specimens showed no difference. The amount of bacteria that adhered to the polishing specimens of zirconia ceramics was significantly lower than that of nickel chromium alloy（P〈0.05）, but no difference was found in the amount of bacteria adhering to the glazing specimens of nickel-chromium alloy and zirconia ceramics. These findings indicate that zirconia ceramics has better ability to inhibit bacterial adhesion than nickel-chromium alloy, especially after glazing.

关 键 词：牙瓷料 铬合金 链球菌科 组织工程 生物材料 口腔生物材料 氧化锆陶瓷 镍铬合金 变形链球菌 细菌黏附性 

分 类 号：R318[医药卫生—生物医学工程]