不同材料支架式可摘局部义齿修复牙列缺损的生物相容性分析  

Different removable partial dentures in repair of dentition defects: a biocompatibility analysis

作　　者：林鸿雷 王月燕[2] 卢阳[2] 

机构地区：[1]海口市人民医院口腔医学中心,海南省海口市570311 [2]海口市人民医院口腔科,海南省海口市570311

出　　处：《中国组织工程研究》2016年第8期1171-1176,共6页Chinese Journal of Tissue Engineering Research

摘　　要：背景:支架式可摘局部义齿是修补牙列缺损的主要方式,其铸造材料主要有纯钛材料、钴铬合金材料及Vitallum 2000材料。目的:分析不同材料支架式可摘局部义齿修复牙列缺损的生物相容性。方法:纳入120例牙列缺损患者,年龄24-68岁,均采用支架式可摘局部义齿进行修复,其中40例采用钴铬合金材料铸造支架式可摘局部义齿,40例采用纯钛材料铸造支架式可摘局部义齿,40例采用Vitallum 2000材料铸造支架式可摘局部义齿。随访2年,对比3组咀嚼效率、凝血情况、血栓、牙槽骨吸收、患者满意度,以及基牙牙周病及继发龋等不良反应发生率。结果与结论:1咀嚼效率与患者满意率:Vitallum 2000材料组>纯钛材料组>钴铬合金材料组(P均<0.05)。2凝血、血栓、牙槽骨吸收发生率:Vitallum 2000材料组<纯钛材料组<钴铬合金材料组(P均<0.05)。3不良反应发生率:Vitallum 2000材料组<纯钛材料组<钴铬合金材料组(P均<0.05)。4表明Vitallium 2000可摘局部义齿修复牙列缺损,可有效降低义齿性口炎、基牙牙周病及继发龋的发生率,保证舒适度、咀嚼力及语言功能。BACKGROUND： Removable partial denture is the main way of repairing dentition defects, and its casting materials mainly include pure titanium, cobalt-chromium alloy and Vitallum 2000. OBJECTIVE： To analyze the biocompatibility of removable partial dentures made of different materials in repair of dentition defects. METHODS： Totally 120 patients with dentition defects, aged 24-68 years old, were enrolled and underwent repair with removable partial dentures. Among these patients, 40 patients were treated with cobalt-chromium alloy-casted removable partial dentures, 40 patients with pure titanium-casted removable partial dentures, and 40 patients with Vitallium 2000 casted removable partial dentures. All patients were followed up for 2 years. The chewing efficiency, coagulation, thrombosis, alveolar bone loss, patient satisfaction, and the incidence of adverse reactions, such as abutments periodontal disease and secondary caries were compared between these three groups. RESULTS AND CONCLUSION：（1） Chewing efficiency and patient satisfaction rate： Vitallum 2000 group titanium group cobalt-chromium alloy group（P〈0.05）.（2） Coagulation, thrombosis, the incidence of alveolar bone loss： Vitallum 2000 group titanium material group cobalt-chromium alloy group（all P〈0.05）.（3） Incidence of adverse reactions： Vitallum 2000 group titanium group cobalt-chromium alloy group（P〈0.05）. These results demonstrate that Vitallium 2000-casted removable partial denture in repair of dentition defects can effectively reduce the incidence of denture stomatitis, abutments periodontal disease and secondary caries, and ensure the comfort of the denture, chewing force and language function.

关 键 词：义齿 铬合金 义齿 局部 组织工程 生物材料 口腔生物材料 可摘局部义齿 牙列缺损 生物相容性 纯钛支架 钴铬支架 Vitallum 2000支架 

分 类 号：R318[医药卫生—生物医学工程]