超高分子质量聚乙烯辐射交联的研究现状  

Irradiation crosslinking of ultra-high molecular weight polyethylene

作　　者：罗淑平[1] 陈云平[2] 黄嘉祐 

机构地区：[1]解放军兰州军区兰州总医院重症医学科,甘肃省兰州市730050 [2]兰州大学口腔医学院,甘肃省兰州市730000 [3]兰州市第三十三中学,甘肃省兰州市730000

出　　处：《中国组织工程研究》2016年第8期1190-1195,共6页Chinese Journal of Tissue Engineering Research

摘　　要：背景:辐射交联可显著提高超高分子质量聚乙烯人工关节的耐磨性,降低磨损率。目的:综述当前国内外超高分子质量聚乙烯辐射交联改性的研究进展。方法:以"UHMWPE,irradiation crosslinking"为检索词,应用计算机检索1995年1月至2012年4月ISI WEB of Knowledge系列数据库,纳入与超高分子质量聚乙烯辐射交联相关的研究。结果与结论:目前国内外超高分子质量聚乙烯辐射交联改性研究主要集中在磨擦性能、耐氧化性和机械性能方面。在高能射线辐照下,超高分子质量聚乙烯内产生自由基,自由基间相互交联。辐射交联改性极大提高了超高分子质量聚乙烯的耐磨性,但却降低了耐氧化性和机械性能。因此,如何在降低磨损率的基础上,提高耐氧化性和机械性能,获得这3种性能平衡的超高分子质量聚乙烯将是今后研究的重点。BACKGROUND： Irradiation crosslinking can remarkably increase the abrasive performance of ultra-highmolecular weight polyethylene（UHMWPE）, thereby reducing its wear rate. OBJECTIVE： To review the recent progress in irradiated crosslinking UHMWPE. METHODS： A computer-based online search of ISI Web of knowledge was performed for articles related to irradiated crosslinking UHMWPE published from January1995 to April 2012 using the keywords of ＂irradiation crosslinking UHMWPE＂ in English. RESULTS AND CONCLUSION： At present, domestic studies on irradiation crosslinking of UHMWPE mainly focus on the wear resistance, oxidation resistance and mechanical properties. Under high-energy radiation, radicals generate from the UHMWPE, which are inter-crosslinked. Irradiation crosslinking dramatically enhances the UHMWPE wear resistance, while reduces its oxidation resistance and mechanical properties. In the future, the research will focus on how to develop new UHMWPE composite with good wear resistance, oxidation resistance and mechanical properties.

关 键 词：聚乙烯 辐射 交联试剂 组织工程 生物材料 材料相容性 超高分子质量聚乙烯 辐射交联 耐氧化性 耐磨性 机械性质能 

分 类 号：R318[医药卫生—生物医学工程]