苯乙烯/丙烯酸载银微球的制备及其抑菌性能的研究  

Preparation and antibacterial performance evaluation of silver loaded styrene/acrylic acid copolymer microsphere

作　　者：黄露露[1] 陈进[1] 孟鸳[1] 张瑜[1] 卢小菊[1,2] 

机构地区：[1]湖北理工学院化学与化工学院,黄石435000 [2]湖北理工学院矿区环境污染控制与修复湖北省重点实验室,黄石435000

出　　处：《化工新型材料》2016年第3期238-240,244,共4页New Chemical Materials

基　　金：国家自然科学基金项目(51402099);湖北省自然科学基金项目(2012FFC018);湖北理工学院校级科研项目(12xjz08R);湖北省高校青年教师深入企业行动计划项目(XD2014679)

摘　　要：以苯乙烯和丙烯酸为单体通过无皂乳液聚合法制备苯乙烯/丙烯酸共聚微球,利用聚乙烯吡咯烷酮为稳定剂和还原剂,在水相中还原硝酸银,银纳米粒子原位还原沉积到微球表面。通过傅里叶变换红外光谱仪(FT-IR)、马尔文粒度分析仪、热重分析仪(TGA)、扫描电子显微镜(SEM)对所得微球的相貌和结构进行了表征;并检测苯乙烯/丙烯酸载银微球的抑菌性能和最小抑菌浓度。结果表明,苯乙烯/丙烯酸载银微球具有形态规整的球形结构;抑菌实验结果表明苯乙烯/丙烯酸载银微球对大肠杆菌、金黄色葡萄球菌和白色念珠菌有明显的抑制作用。Styrene/acrylic acid copolymer microspheres were prepared by soap-free emulsion polymerization using styrene and acrylic acid as monomer.Then PVP acted as a stabilizer and reducing agent in the aqueous phase reduction of silver nitrate,silver nanoparticles deposited in situ reduction surface of the microspheres.The products were studied by fourier transform infrared spectroscopy（FT-IR）,Malvern particle analyzer,thermal-gravimetric analysis（TGA）and scanning electron microscopy（SEM）.And detected the bacteriostatic action and the minimal inhibitory concentrations（MIC）of PSA/Ag microspheres.The results showed that PSA/Ag microspheres were regularly spherical.PSA/Ag microspheres exhibited good antibacterial properties against E.coli,S.aureus and Candida albicans.

关 键 词：苯乙烯/丙烯酸共聚微球 无皂乳液聚合 银纳米粒子 抑菌性能 

分 类 号：TQ316.334[化学工程—高聚物工业]