某院2014年191例药品不良反应监测报告情况分析  

Analysis of ADR Reports in a Hospital in 2014

作　　者：杨丽萍[1,2] 王国俊 

机构地区：[1]四川医科大学,四川泸州646000 [2]四川省自贡市第三人民医院,四川自贡643020

出　　处：《中国药业》2016年第5期65-67,共3页China Pharmaceuticals

摘　　要：目的分析某院药品不良反应(ADR)的发生和监测报告的特点及规律,为临床安全用药、合理用药提供参考。方法对某院2014年ADR报告191例进行分类、统计和分析。结果 191例ADR中,以60岁及以上年龄段发生率最高(59.16%);给药途径以静脉给药最多(60.73%);ADR涉及药品113种,以抗肿瘤药物及抗感染药物为主;ADR累及器官或系统多为胃肠系统损害(47例)及皮肤附件损害(43例);新的或严重的ADR 22例(11.52%)。结论医务人员应重视ADR监测工作,尤应加强新的一般和严重类型ADR的监测,选择适宜给药途径,特别关注特殊人群如60岁以上年龄的患者。应提高甄别能力和处置水平,避免或减少ADR的发生,保障患者用药安全。Objective To analyze the characteristics and regularity of ADRs in a hospital and to promote the rational drug use in the clinical practice. Methods 191 cases of ADR reports in the hospital in 2014 were collected. The relevant data was classified and sta-tistically analyzed according to age, gender, ADR involved organs, drugs, and route of drug administration. Results Among the 191 cases of ADR, the most ADR cases occurred in the age group of above 60 years old, accounting for 59. 16%; about 60. 73% were induced by intravenous administration; among the 113 varieties of drugs involved in ADRs were anticancer drugs and anti- infective drugs. The main clinical manifestations were digestive system injury（ 47 cases） and lesion of skin（ 43 cases）; new or serious ADR were 22 cases（ 11. 52%）. Conclusion More importance should be attached to ADR collection and reporting work in clinical practice, and the selection of appropriate route of drug administration should be strengthened and more pharmaceutical care should be given to the key groups of people such as over 60 years old people.

关 键 词：药品不良反应 监测报告 合理用药 

分 类 号：R969.3[医药卫生—药理学] R954[医药卫生—药学]