呼吸运动锻炼联合营养支持治疗慢性阻塞性肺疾病的临床疗效观察  

Clinical Effect of Breathing Exercise Combined With Nutrition Support on Chronic Obstructive Pulmonary Disease

作　　者：李永强[1] 

机构地区：[1]广东省佛山市南海区第二人民医院呼吸内科,528251

出　　处：《实用心脑肺血管病杂志》2016年第3期107-110,共4页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

摘　　要：目的观察呼吸运动锻炼联合营养支持治疗慢性阻塞性肺疾病(COPD)的临床疗效。方法选取佛山市南海区第二人民医院2013年1月—2015年1月收治的COPD患者180例,按照入院顺序分为对照组90例和治疗组90例,然后采用随机单盲设计法将治疗组患者分为A、B、C 3个亚组,每组30例。对照组患者给予常规治疗;在常规治疗基础上,A组患者给予呼吸运动锻炼,B组患者给予营养支持,C组患者给予呼吸运动锻炼联合营养支持。比较各组患者治疗前和治疗3个月后肺功能〔第一秒用力呼气容积占预计值百分比(FEV_1%)和第一秒用力呼气容积占用力肺活量的百分比(FEV_1/FVC)〕、血气分析指标〔动脉血氧分压(PaO_2)和动脉血二氧化碳分压(Pa CO2)〕及生存质量〔圣乔治呼吸问卷(SGRQ)评分和6分钟步行距离(6MWD)〕。结果治疗前4组患者FEV_1%、FEV_1/FVC、PaO_2及Pa CO2比较,差异无统计学意义(P>0.05)。治疗后A、B、C 3组患者FEV_1%、FEV_1/FVC、PaO_2高于对照组,Pa CO2低于对照组(P<0.05);C组患者FEV_1%、FEV_1/FVC、PaO_2高于A组和B组,Pa CO2低于A组和B组(P<0.05)。治疗前4组患者SGRQ评分和6MWD比较,差异无统计学意义(P>0.05)。治疗后A、B、C 3组患者SGRQ评分高于对照组,6MWD长于对照组(P<0.05);C组患者SGRQ评分高于A组和B组,6MWD长于A组和B组(P<0.05)。结论在常规治疗基础上应用呼吸运动锻炼联合营养支持治疗COPD的临床疗效确切,能有效改善患者肺功能,提高生存质量。Objective To observe the clinical effect of breathing exercise combined with nutrition support on chronic obstructive pulmonary disease. Methods From January 2013 to January 2015,a total of 180 patients with chronic obstructive pulmonary disease were selected in the Second People’s Hospital of Nanhai District,Foshan,and they were divided into control group and treatment group according to visiting sequence,each of 90 cases; according to single- blind- random principle,patients of treatment group were divided into three subgroups： A group,B group and C group,each of 30 cases. Patients of control group received conventional treatment after admission,of A group received extra breathing exercise based on conventional treatment,of B group received extra nutrition support based on conventional treatment, while patients of C group received breathing exercise combined with nutrition support based on conventional treatment. Lung function index（ including FEV1% and FEV1/ FVC）,blood- gas analysis index（ including PaO2 and Pa CO2） and survival quality（ including SGRQ score and 6-minute walk distance） before treatment and after 3 months of treatment were compared between the two groups. Results No statistically significant differences of FEV1%,FEV1/ FVC,PaO2 or Pa CO2 was found among control group,A group,B group and C group before treatment（ P 〉 0. 05）. After treatment,FEV1%, FEV1/ FVC and PaO2 of A group, of B group, of C group were statistically significantly higher than those of control group,while Pa CO2 of A group,of B group,of C group was statistically significantly lower than that of control group（ P 〈 0. 05）; FEV1%, FEV1/ FVC and PaO2 of C group were statistically significantly higher than those of A group,of B group,while Pa CO2 of C group was statistically significantly lower than that of A group,of B group,respectively（ P 〈 0. 05）. No statistically significant differences of SGRQ score or 6- minute walk distance was found among control group,A group,B group and C group before trea

关 键 词：肺疾病 慢性阻塞性 呼吸运动锻炼 营养支持 治疗结果 

分 类 号：R563.9[医药卫生—呼吸系统]