评价双环醇治疗肾病综合征合并药物肝损害的疗效与安全性  

Evaluation of the Efficacy and Safety of Double Loop Alcohol in the Treatment of Nephrotic Syndrome With Drug Induced Liver Injury

作　　者：马可 李银辉 

机构地区：[1]一汽总医院肾内科,长春130000

出　　处：《中国继续医学教育》2016年第7期155-156,共2页China Continuing Medical Education

摘　　要：目的为了进一步探究双环醇对肾病综合征合并药物肝损害的治疗效果与药物安全性。方法根据我院2013年1月~2015年12月所收治的74例肾病综合征合并药物肝损害患者的临床治疗资料,随机将全部患者分为治疗组（口服双环醇片）和对照组（口服多烯磷脂酰胆碱胶囊）,每组各有患者37人,治疗期限均为3个月,对比两组患者各项肝功和血清指标以及药物副作用的产生情况。结果对比两组患者肝功能、治疗效果治疗组优于对照组,其对比结果差异具有统计学意义（P〈0.05）。两组患者在治疗过程中均未出现药物副作用。结论双环醇是近年来使用效果较好、治疗效率较高、药物副作用较小的一种肾病综合征合并药物肝损害的治疗药物,且其药效起效快、药力持续时间长,且无过多的用药限制。Objective To explore the therapeutic efficacy and safety of double loop alcohol in the treatment of nephritic syndrome complicated with drug induced liver damage. Methods According to our hospital from January 2013 and December 2015 of 74 cases of nephritic syndrome complicated with drug-induced liver injury patients randomly were divided into the treatment group（bicycle） and control group（oral polygene phosphatidylcholine capsules） and 37 cases in each group, treatment for 3 months. Results Compared with the two groups of patients with liver function, treatment effect, the treatment group was significantly better than the control group, with statistical significance（P〈0.05）. There were no side effects in the treatment. Conclusion It is effective to treat the drug with high efficiency and little side effect, the effect of the drug is fast, the duration is long, the drug is not limited.

关 键 词：双环醇 多烯磷脂酰胆碱 肾病综合征 药物肝损害 治疗效果 

分 类 号：R965[医药卫生—药理学]