早期介入栓塞治疗脑动脉瘤破裂80例的效果及预后  

Effect and prognosis of early interventional embolization in the treatment of cerebral aneurysm rupture based on 80 patients

作　　者：焦松[1] 姚声涛[1] 李刚[1] 韩冲[1] 夏湘平[1] 曾尤超[1] 肖华[1] 唐钧[1] 刘锐[1] 

机构地区：[1]遵义医学院附属医院脑血管科,贵州遵义563003

出　　处：《中国医药科学》2016年第4期127-129,共3页China Medicine And Pharmacy

摘　　要：目的探讨早期介入栓塞治疗对脑动脉瘤破裂的治疗效果及预后,为今后脑动脉瘤的治疗提供临床价值。方法选择本院2013年6月~2015年6月收治的80例脑动脉瘤患者随机分为治疗组和对照组,且均实施微弹簧圈介入栓塞治疗。其中治疗组的40例患者在入院3d内进行介入治疗,而对照组的另外40例患者则在入院3d后进行介入治疗。术后进行随访6个月,比较两组患者在手术后的栓塞效果、并发症情况,并利用改良Rankin表（m RS）评分进行疗效分析。结果治疗组完全栓塞率达85.0%,远超于对照组的62.5%;且治疗组的次全栓塞率和不完全栓塞率远低于对照组（P〈0.05）;治疗组术后6个月的m RS评分低于对照组（P〈0.05）;数据显示对照组并发症发生率为82.5%,明显高于治疗组的15%,差异均有统计学意义（P〈0.05）。结论早期介入栓塞在脑动脉瘤破裂中具有良好的治疗效果和预后,值得推广应用。Objective To explore the effect and prognosis of early interventional embolization in treating aneurysm rupture and provide clinical reference for its treatment in the future. Methods 80 patients with cerebral aneurysm who were in our hospital from June 2013 to June 2015 were randomly divided into treatment group and control group, 40 cases in each group, all patients received interventional embolization with micro-coil. The treatment group received interventional therapy within 3 days of admission, while the control group received interventional therapy 3 days after admission. All patients were followed up for 6 months, the embolization effect and complication incidences of the two groups were compared and analyzed by modified Rankin scale（m RS）. Results In the treatment group, the excellent embolization rate reached 85.0%, which was far better than the 62.5% of the control group, while the second-excellent and incomplete embolization rates were obviously lower than those of the control group（P 0.05）. The m RS scores in the treatment group 6 months after treatment were lower than those of the control group（P 0.05）. Data indicated that the complication rate of the control group was 82.5%, which was obviously higher than the 15% of the treatment group. All differences shown above were statistically significant（P 0.05）. Conclusion Early interventional embolization has good therapeutic effect and prognosis in the treatment of cerebral aneurysm rupture, which is worthy of popularization.

关 键 词：脑动脉瘤 介入栓塞 预后 

分 类 号：R651.12[医药卫生—外科学]