抗菌肽在断奶仔猪饲粮中的应用效果研究  

The Research and Application of Plant Extract in Piglets

作　　者：朱宇旌[1] 王博[1] 李方方[1] 郑丽莉[1] 高原 孟玲 郭福来 丁兰 张勇[1] 

机构地区：[1]沈阳农业大学畜牧兽医学院,辽宁沈阳110866 [2]辽宁德宝农牧集团有限公司,辽宁沈阳110171 [3]沈阳福康农牧科技有限公司,辽宁沈阳110164

出　　处：《养猪》2016年第2期17-20,共4页Swine Production

基　　金：国家自然科学基金(31440082和31101253)

摘　　要：为研究抗菌肽（AMPs）在仔猪生产中的应用效果,选取（10.30±1.13）kg大白仔猪180头,随机分为3组,每组4个重复,每个重复15头,对照组饲喂基础饲粮,试验组分别在基础饲粮中添加抗菌肽A（AMPs-A）500 mg/kg和抗菌肽B（AMPs-B）300 mg/kg,试验期28 d。结果表明：1）AMPs-A组在试验1~14 d、15~28 d、1~28 d这3个时间阶段日增重比对照组分别提高5.66%（P〉0.05）、3.92%（P〉0.05）、3.85%（P〉0.05）。2）AMPs-A组血清尿素氮水平比对照组降低14.55%（P〈0.01）。3）与对照组相比,AMPs-A、AMPs-B血液中Ig G分别提高2.07%（P〈0.05）、1.27%（P〈0.05）,血清总蛋白水平分别提高4.48%（P〈0.05）、4.03%（P〈0.05）,血液T淋巴细胞转化率AMPs-A组提高39.02%（P〈0.05）。4）AMPs-A组干物质、粗蛋白质和粗脂肪消化率分别比对照组提高2.62%（P〈0.05）、3.95%（P〈0.05）、3.70%（P〈0.05）。5）肠道中大肠杆菌数,AMPs-A、AMPs-B比对照组分别降低5.53%（P〈0.05）、3.77%（P〈0.05）;乳酸杆菌数,AMPs-A、AMPs-B比对照组分别提高4.94%（P〈0.05）、3.67%（P〈0.05）;双歧杆菌数,AMPs-A、AMPs-B比对照组分别提高5.61%（P〈0.05）、4.75%（P〈0.05）。综上所述,在仔猪饲粮中添加AMPs可以有效提高仔猪的生长性能、饲料养分消化利用率,改善血清生理生化指标水平、肠道微生物平衡。综合本试验各项指标,仔猪饲粮中添加AMPs-A效果较好。This test was designed to study the effects of antimicrobial peptides（AMPs） in pig production. 180 pigs（10.30±1.13） kg had been randomly divided into 3 groups,and each group 4 repeats,each repeat 15 pigs.The control group was fed based diet,the experimental group were fed basic feeding food with 500 mg/kg AMPs-A and300 mg/kg AMPs-B.Experiment lasted for 28 days.Results showed that：1）compared with control group,ADG re-spectively increase 5.66%（P〉0.05）,3.92%（P〉0.05）,3.85%（P〉0.05） the day of 1 ~14,15~28,1~28 in AMPs-A.2）AMPs-A dramatically significantly reduce BUN 14.55%（P〈0.01）. 3）compared with control group,the Ig G of AMPs-A and AMPs-B had increased 2.07%（P〈0.05） and 1.27%（P〈0.05）;the TP of AMPs-A and AMPs-B had increased 4.48%（P〈0.05） and 4.03%（P〈0.05）;and AMPs-A significantly increased T lymphatic conversion rates39.02%（P〈0.05） in blood.4）AMPs-A respectively significantly increased DM,CP and EE absorption rate 2.62%（P〈0.05）,3.95%（P〈0.05）,3.70%（P〈0.05）.5）E. coli colony count in pig feces had decreased 5.53%（P〈0.05） and3.77%（P〈0.05） in AMPs-A and AMPs-B.Lactobacillus in AMPs-A and AMPs-B has increased 4.94%（P〈0.05）and 3.67%（P〈0.05）,and Bifidobacterium colony count of AMPs-A and AMPs-B had increased 5.61%（P〈0.05）and 4.75%（P〈0.05）.Adding AMPs in daily diet can effectively improve pig growth performance,blood physiological and biochemical indicators feed digestion utilization and improve intestinal microbial balance.The test indicate that adding AMPs-A is better than AMPs-B.

关 键 词：抗菌肽 断奶仔猪 生长性能 血清生理生化指标 养分消化率 粪便微生物菌群 

分 类 号：S828.5[农业科学—畜牧学]