郴州地区解脲脲原体感染者耐药情况分析  

Antimicrobial susceptibility analysis of ureaplasma urealyticum in patients with urinary tract infectious patients in Chenzhou

作　　者：李佳艳[1] 罗良贤[1] 袁红霞[1] 江杨华[1] 单斌[1] 任群峰[1] 向璟 代国知[1] 陈虹亮[1] 

机构地区：[1]郴州市第一人民医院,湖南郴州423000

出　　处：《临床医药实践》2016年第4期281-282,315,共3页Proceeding of Clinical Medicine

摘　　要：目的:探讨泌尿生殖道解脲脲原体(Uu)对8种常用抗生素的耐药情况。方法:采用Uu培养、鉴定、药敏一体化试剂盒,对郴州地区2 710例泌尿道感染患者的泌尿生殖道分泌物进行Uu培养及药敏试验。结果:药敏试验表明,Uu对红霉素耐药率最高,达30.52%,其余依次为罗红霉素、阿奇霉素、克拉霉素、左氧氟沙星、司帕沙星、多西环素、米诺环素,耐药率分别为17.52%,14.10%,13.43%,6.97%,5.28%,3.95%,2.80%。结论:Uu对红霉素等多种抗生素高度耐药,治疗上应首选半合成四环素类,同时应规范临床经验性治疗用药,进一步加强对Uu菌株耐药变迁的监测。Objective： To investigate the antimicrobial susceptibility analysis of Ureaplasma urealyticum（ Uu） patients in Chenzhou. Methods： Urinary tract secretion from 2710 patients with infertility were cultured for Uu,whilst whose antimicrobial susceptibility were tested. Results： Our data suggested that the most resistant antimicrobial drug was Erythrocin,whose resistance rate was up to 30. 52%,and resistance rates for the rest 7 antimicrobial drug was roxithromycin（ 17. 52%）,azithromycin（ 14. 10%）,clarithromycin（ 13. 43%）,levofloxacin（ 6. 97%）,sparfloxacin（ 5. 28%）,doxycycline（ 3. 95%）,minocycline（ 2. 80）. Conclusion： Uu showed high resistance to Erythrocin and other antimicrobial drugs,so,empiric treatment should be standardized in clinical medicine,and further monitoring the resistance changes of Uu were needed.

关 键 词：解脲脲原体 药敏试验 生殖道感染 

分 类 号：R693.1[医药卫生—泌尿科学]