低能量激光对2型糖尿病合并慢性牙周炎患者血糖代谢指标及超敏C反应蛋白的影响  

Effect of low 1evel laser treatment on metabolic control and high-sensitivity C-reactive protein of type 2 diabetes mellitus combined chronic peridontitis patients

作　　者：李萌萌[1] 赵燕娟[1] 祝书金 李荣华[1] 

机构地区：[1]天津市第一中心医院口腔科,300192 [2]天津市中医药大学第一附属医院口腔科,300192

出　　处：《国际生物医学工程杂志》2016年第1期24-27,共4页International Journal of Biomedical Engineering

基　　金：天津市卫生局科技基金资助项目，Science and Technology Fund of Health Bureau of Tianjin

摘　　要：目的 观察低能量激光疗法（LLLT）对2型糖尿病合并慢性牙周炎（DMCP）患者牙周临床指标、血清超敏C反应蛋白（hs-CRP）和血糖代谢指标的影响,探讨低能量激光的干预疗效.方法 选择90例DMCP患者,随机分为A组（基础治疗）、B组（基础治疗＋LLLT）及C组（对照组）3组,于治疗前、治疗后3个月时分别检测3组患者牙周指数（牙周探诊深度（PD）、临床附着丧失（CAL）、龈沟出血指数（SBI））、hs-CRP、糖化血红蛋白（HbA1c）及空腹血糖（FPG）水平,并分析、比较其变化.结果 治疗后A、B两组的PD、CAL、SBI及hs-CRP均有所改善,其差异有统计学意义（P＜0.05）,其中B组效果更为显著（P＜0.01）;A、B两组HbA1c、FPG水平呈下降趋势,其中B组差异有统计学意义（P＜0.05）.结论 LLLT对于DMCP患者可显著控制其牙周炎症、降低血清hs-CRP水平及改善血糖水平,并预防糖尿病并发症的发生.Objective To investigate the effect of low 1evel laser treatment （LLLT） on periodontal clinical index,high-sensitivity C-reactive protein （hs-CRP） and metabolic control in patients of type 2 diabetes mellitus combined chronic peridontitis.Methods Nighty patients with type 2 diabetes combined chronic peridontitis were divided into three groups：initial periodontal therapy （group A）,initial therapy combined with LLLT （group B） and control group （group C）.The periodontal clinical parameters including periodontal probing depth （PD）,clinical attachment loss （CAL）,sulcus bleeding index （SBI）,hs-CRP,HbA1c and fasting blood glucose （FBG） were tested before and at three months after therapy.Results The periodontal clinical parameters （PD,CAL,SBI） and hsCRP in group A and B improved significantly compared with that of group C after therapy （P〈0.05）,with group B had more significant difference （P〈0.01）.For the levels of HbA1c and FPG,group A and B showed downtrend,and more obvious outcome was detected in group B （P〈0.05）.Conclusions LLLT can effectively improve periodontal status,hs-CRP levels and metabolic control of patients with type 2 diabetes combined with chronic peridontitis,and thus to prevent the occurrence of diabetes complications.

关 键 词：牙周炎 低能量激光疗法 2型糖尿病 超敏C反应蛋白 

分 类 号：R544.1[医药卫生—心血管疾病]