代谢综合征体型指标与中医气阴两虚及痰瘀证关系的系统综述及Meta分析  

Relation of somatotype index of metabolic syndrome patients between syndrome of deficiency of both qi and yin and phlegm with blood stasis: A systematic review and Meta-analysis

作　　者：闫旭[1] 闫小光[2] 张军[2] 吴翥镗[2] 李怡[2] 

机构地区：[1]北京中医药大学第一临床医学院,北京100700 [2]北京医院,北京100730

出　　处：《中华中医药杂志》2016年第4期1249-1252,共4页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：2011年国家临床重点专科建设项目~~

摘　　要：目的:分析代谢综合征(MS)患者体型指标与痰瘀证、气阴两虚证的关系。方法:检索中国知网、万方、维普数据库从建库至2014年12月的所有相关文献,语种为中文和英文;3位独立研究者筛选相关文献,提取数据,进行质量评价,并使用Review Manager 5.3软件对研究结果进行合并分析,并系统综述。结果:共纳入8篇研究,其中8篇研究均对体质量指数(BMI)进行了研究,其中3篇研究对比了腰围(WC),仅1篇研究对比了腰臀比(WHR)。所有文献经质量评价,分值9至13分,质量欠佳。经Meta分析提示痰瘀证组BMI、WC高于气阴两虚组,危险指数分别为2.24,95%CI[1.60,2.89]及4.15,95%CI[2.55,5.75],并经敏感性分析验证。结论:根据有限的证据,痰瘀证MS患者肥胖程度较气阴两虚证者为甚。Objective： To analyze the relation of somatotype index of Metabolic syndrome（MS） between TCM syndrome of phlegm with blood stasis and deficiency of both qi and yin. Methods： Related articles from prior to December 2014 were searched from the database including CNKI, Wanfang DATA, and VIP, and the language were limited to Chinese/English. The data from retrieved articles were evaluated by three independent reviewers, and then analyzed by Review Manager 5.3 meta-analysis software in systematic review. Results： Eight researches were included. The quality index of these researches was between nine and thirteen. All of eight researches reported the relation in BMI, where three were in WC, only one in WHR. By Meta-analysis, the phlegm with blood stasis group was higher than deficiency of both qi and yin group in BMI（relative risk was 2.24; 95%CI[1.6, 2.89]） and in WC（relative risk was 4.15; 95%CI[2.55, 5.75]）. Conclusion： According to the limited evidence, the somatotype index of MS patients with syndrome of phlegm with blood stasis was worse than deficiency of both qi and yin.

关 键 词：代谢综合征 体型 痰瘀 气阴两虚 META分析 系统综述 

分 类 号：R259[医药卫生—中西医结合]