基于聚类分析及主成分分析的糖尿病肾病中医四诊信息特征临床研究  

Clinical study on four TCM diagnostic information characteristics of diabetic nephropathy based on cluster analysis and principal component analysis

作　　者：王养忠[1] 柳红芳[1] 张先慧[1] 许家骏[1] 杭海燕[1] 姜旻[1] 张向伟[1] 韩锦丹 

机构地区：[1]北京中医药大学东直门医院,北京100700

出　　处：《中华中医药杂志》2016年第4期1416-1419,共4页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：北京中医药大学自主课题资助项目(No.2015-JYB-JSMS071)~~

摘　　要：目的:探索应用聚类分析及主成分分析方法研究糖尿病肾病(DN)中医四诊信息特征。方法:采集120例2014年3月-2015年2月收治的明确诊断DN的120例患者中医证候信息,在线录入,建立数据库,运用聚类分析、主成分分析探索性研究其四诊信息特征。结果:经聚类分析及主成分分析后,将DN分为4类:气阴两虚证、热盛气滞血瘀兼气虚证、血虚兼阴虚气滞证、湿热兼血虚阳虚证。结论:应用聚类分析及主成分分析研究方法能够在一定程度上反映DN的中医四诊信息特征。Objective： To explore the clinical characteristic of four TCM diagnostic information of diabetic nephropathy based on cluster analysis and principal component analysis. Methods： The TCM diagnostic information of 120 cases of patients with diabetic nephropathy were prospectively observed and collected from March 2014 to February 2015. The database was established by online entry, where the characteristics of four TCM diagnostic informations were explored. The main disease and syndrome characteristics were analyzed by cluster analysis and principal component analysis. Results： After the cluster analysis and principal component analysis, DN was divided into four categories： syndrome of deficiency of both qi and yin, syndrome of intense heat, qi stagnation and blood stasis with qi deficiency, syndrome of blood deficiency with yin deficiency and qi stagnation, syndrome of dampness-heat with blood deficiency and yang deficiency. Conclusion： The cluster analysis and principal component analysis could reveal the clinical characteristic of four TCM diagnostic information of diabetic nephropathy in a certain extent.

关 键 词：糖尿病肾病 聚类分析 主成分分析 中医四诊 

分 类 号：R259[医药卫生—中西医结合]