88例结节病临床分析  

A retrospective clinical analysis of 88 cases with sarcoidosis

作　　者：貊婷婷 杨海峰[1] 黄海[1] 聂蔚[1] 李兵[1] 

机构地区：[1]解放军第二军医大学附属长征医院呼吸内科,上海200003

出　　处：《国际呼吸杂志》2016年第3期188-191,共4页International Journal of Respiration

基　　金：上海市科学技术委员会科研计划项目（134119a0100）

摘　　要：目的：总结结节病临床特点,提高对结节病的认识。方法回顾性分析88例结节病患者临床资料。结果88例结节病患者男女比例为1∶1.44,平均年龄为（49.69±11.84）岁。临床表现主要为咳嗽、胸闷、消瘦、浅表淋巴结肿大。肺部浸润表现以小结节居多,其次是斑片状阴影。63.33%的患者出现血清血管紧张素转换酶（SACE）升高。病理检查以纵隔镜、胸腔镜和皮损处活检确诊率最高。结论结节病临床表现缺乏特异性,SACE 升高较常见,纵隔镜、胸腔镜和皮损处活检是病理确诊结节病的主要方法。Objective To summarize the clinical characteristics of sarcoidosis and to improve our understanding of sarcoidosis.Methods Review and analyze the clinical data of 88 sarcodiosis patients. Results The male and female ratio in 88 sarcoidosis patients was 1 ∶ 1.44 and their average age was 49.69±1 1.84.The main clinical manifestations were cough,choking sensation in chest,marasmus,and superficial lymph node enlargement.The patients with feinsilver and fein always had excessive small nodules or patchy shadows.63.33% of patients had the symptom of rising serumangiotensin-converting enzyme（SACE）.In pathological examination,mediastinoscopy,thoracoscopy,and biopsy of skin lesions had the highest diagnosis rate.Conclusions The clinical manifestations of sarcoidosis have no specificity;the rising of SACE is common;mediastinoscopy,thoracoscopy,and biopsy of skin lesions are the main methods to diagnose sarcoidosis pathologically.

关 键 词：结节病 临床特点 血清血管紧张素转化酶 

分 类 号：R593.9[医药卫生—内科学]