mTORC2 is a tyrosine kinase  被引量:1

mTORC2 is a tyrosine kinase

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作  者:Xuemin Wang Christopher G Proud 

机构地区:[1]Nutrition and Metabolism Theme, South Australian Health & Medical Research Institute, North Terrace, and University of Adelaide, Adelaide, Australia

出  处:《Cell Research》2016年第1期1-2,共2页细胞研究(英文版)

摘  要:The mammalian target of rapamycin (mTOR), a protein kinase, is the centre of huge attention due to its importance in intraceliular signaling and in health and disease. In their recent study, Yin et al. show that mTOR can regulate signaling through the insulin-like growth factor 1 receptor and that it possesses a new enzymatic activity -the ability to phosphorylate nroteins on tvrosine residues.

关 键 词:酪氨酸激酶 细胞内信号转导 胰岛素样生长因子1 MTOR 雷帕霉素 哺乳动物 蛋白激酶 靶蛋白 

分 类 号:Q73[生物学—分子生物学] Q257

 

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