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作 者:霍亚南[1]
出 处:《中华内分泌代谢杂志》2016年第3期213-216,共4页Chinese Journal of Endocrinology and Metabolism
基 金:国家代谢性疾病临床医学研究中心(2013BA109813);科技部重大新药创制项目(2012zx09303006J001)
摘 要:目的了解社区中老年人颈围与心血管危险因素的相关性。方法对社区4JD岁及以上居民9665名进行问卷调查,检测身高、体重、颈围、腰围、血压、血脂、血糖、HbAic空腹胰岛素等。采用SPSS16.0进行统计学分析。结果(1)无论男女,颈围与腰围、体重指数、血压、血糖、低密度脂蛋白胆固醇、三酰甘油和胰岛素抵抗指数均呈正相关、与高密度脂蛋白胆固醇呈负相关(均P〈0.05);男性颈围与总胆固醇呈正相关(P〈0.01),女性颈围与总胆固醇不相关(P〉0.05)。(2)男性颈围增大会增加糖尿病的发生风险(OR=1.14,95%C11.02~1.28):女性颈围增大会增加高血压(OR=1.17,95%Cl 1.08—1.27)、糖尿病(OR=1.24,95%CI1.13~1.37)、血脂异常(OR=1.17,95%CI1.09~1.27)和胰岛素抵抗(OR=1.15,95%CI1.06—1.26)的发生风险。在女性颈围影响较男性更大。结论颈围是心血管危险因素独立关联的指标。Objective To investigate the relationships between the neck circumference and cardiovascular risk factors of middle-aged and elder people in a community. Methods Altogether 9 665 community residents ( age ≥ 40 years) were enrolled in the present study. The height, weight, neck circumference, waist circumference, blood pressure, total cholesterol, triglycerides, low density lipoprotein-cholesterol ( LDL-C ) , high density lipoprotein- cholesterol ( HDL-C), blood glucose, glycosylated hemoglobin, and fasting insulin were measured, and documented in the questionnaire along with other basic information. After adjusted for age, Pearson correlation coefficient was used to analyze the relationship between the neck circumference and the binary variables of cardiovascular risk factors. SPSS 16.0 software was used for statistical analysis. Results ( 1 ) The neck circumferences were ( 37.11± 2.79 ) cm in male and ( 32.79 ± 2.31 ) cm in female ; which were higher in males than females. In both males and females, after adjusted for age, the neck circumference was positively correlated to waist circumference, body mass index, blood pressure, plasma glucose, LDL-C, triglycerides, and insulin resistance, the neck circumference was negatively correlated to HDL-C ( all P〈0.05 ) ; The neck circumference of males was positively correlated to total cholesterol ( P〈 0.01 ) ; The neck circumference of females was not correlated with total cholesterol ( P〉0.05 ). ( 2 ) After adjusted for body mass index and the waist circumference, the neck circumference of males increased with the risk of diabetes ( OR= 1.14, 95% CI 1.02-1.28 ) ; while the higher neck circumference of females increased the risk of hypertension ( OR = 1.17, 95% C1 1.08-1.27 ), diabetes ( OR = 1.24,95% C11.13-1.37 ), dyslipidemia ( OR = 1.17,95% C1 1.09-1.27) , and insulin resistance ( OR = 1. 15, 95% CI 1.06-1.26). The neck circumference exerted higher impact on women than it did on men. Conclusion Th
分 类 号:R54[医药卫生—心血管疾病]
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