正交设计优选风芍六君子汤的提取工艺  

Optimization of Fengshao Liujunzi Decoction Extraction Technology by Orthogonal Design

作　　者：李柏群[1] 刘骏[2] 陈绍成[3] 彭腾[4] 黄道秋[1] 薛梅[2] 

机构地区：[1]重庆三峡中心医院,重庆404000 [2]重庆市北碚区中医院,重庆400711 [3]重庆第二师范学院,重庆400067 [4]成都中医药大学,四川成都611137

出　　处：《中国药业》2016年第6期26-29,共4页China Pharmaceuticals

基　　金：重庆市2010年科技攻关项目;项目编号:CSTC;2010AC5095

摘　　要：目的优化风芍六君子汤的提取工艺。方法采用正交设计试验法,考察不同提取工艺制备的风芍六君子汤中芍药苷和橙皮苷的含量及出膏率,并依据试验数据设计最佳提取工艺。结果最佳提取工艺为加10倍量水,提取2次,每次1 h。结论优选出的提取工艺简便、经济、提取效率高。Objective To optimize the extracting technology for Fengshao Liujuzi Decoction.Methods Orthogonal design method was used to detect the content and the ratio of extraction of peoniflorin,aurantiamarn in Fengshao Liujuzi Decoctionm,and to design the best extracting method according to the results.Results The best extracting method was 10 times of water,decocted for 2 times,and1 h for each time.Conclusion The optimized extracting method is effective and cheap,easy to operate,and highly efficient.

关 键 词：正交设计 风芍六君子汤 芍药苷 橙皮苷 提取工艺 

分 类 号：TQ461[化学工程—制药化工] R284.1[医药卫生—中药学]