儿科门诊超说明书用药处方调查与分析  

Investigation and Analysis on Off-Label Drug Use in Pediatric Outpatients

作　　者：谢洪梅[1] 钱青[1] 张蓉[1] 

机构地区：[1]中国人民解放军第三军医大学第二附属医院,重庆400037

出　　处：《中国药业》2016年第6期78-80,共3页China Pharmaceuticals

摘　　要：目的了解儿科门诊超说明书用药情况,为开展儿科药学服务、促进儿童安全用药提供依据。方法通过对某院儿科门诊处方进行抽查,随机抽取某院儿科门诊2015年1月处方900张,对药物使用情况及超说明书用药情况进行统计和分析。结果儿科门诊超说明书用药发生率为28.00%,有11种药物出现超说明书用药。呼吸系统疾病处方抽取最多,超说明书用药比例为34.57%。感染性疾病处方量相对较少,但超说明书用药比例最高,占39.13%。超说明书用药类型最多的为超年龄(45.24%)和超适应证(43.65%)。结论该院儿科门诊中多种药物存在超说明书使用现象,医生在临床用药过程中应密切观察患儿的生命体征,以防出现药品不良反应。Objective To understand the situation of off-label drug use in pediatric outpatients,and to provide references for carrying out pediatric pharmaceutical care and promote the safe medication of children.Methods The prescriptions of pediatrics outpatient department in the hospital were checked,900 prescriptions in January 2015 were randomly selected.The off-label drug use was investigated,analyzed and commented.Results The incidence rate of off-label drug use in this hospital was 28.00% and 11 kinds of drugs had off-label drug use in the investigation.The prescription of respiratory system disease was the most of all,with the 34.57%incidence rate of off-label drug use.The amount of infectious diseases was relatively small,but the ratio was the highest as 39.13%.The main categories of off-label drug use were exceeding pediatric information of age（45.24%） and exceeding indication（43.65%）.Conclusion The phenomenon of pediatric outpatient off-label drug use exists in multiple drugs in the hospital.Doctors should ob-serve the vital signs of the children closely during the clinical medication in order to prevent drug reactions.

关 键 词：超说明书用药 处方分析 儿科 

分 类 号：R969.3[医药卫生—药理学] R451[医药卫生—药学]