光动力治疗中、重度痤疮的疗效观察及护理  

Observation and nursing of moderate-severe acne treated by photodynamic therapy

作　　者：李艳[1] 王芳[1] 徐春兴[1] 张汝芝[1] 

机构地区：[1]江苏省常州市第一人民医院皮肤科,江苏常州213003

出　　处：《中国现代医生》2016年第8期157-160,共4页China Modern Doctor

摘　　要：目的观察5-氨基酮戊酸光动力疗法对于中、重度痤疮的临床疗效,并评估其安全性及采取相应的护理措施。方法 2014年10月～2015年6月80例患者进行艾拉光动力治疗。应用新鲜配置5%的5-氨基酮戊酸凝胶均匀涂抹于皮损处,避光封包1～2 h后,让患者戴护目镜后接受633 nm LED红光照射20 min,随后冷喷20 min。治疗结束后,严格避光48 h。每2周治疗1次,1个疗程3～4次。随访6个月,治疗后进行疗效判定。结果 80例中重度痤疮中,治愈53例（66.25%）,显效10例（12.50%）,好转10例（12.50%）,无效7例（3.75%）,总有效率达91.25%。32例患者出现局部轻中度可耐受性红斑,无永久性炎症后色沉。结论应用5%的5-氨基酮戊酸光动力治疗中重度痤疮,联合有效护理,临床效果满意、不良反应少。Objective To investigate the clinical efficacy and safety of aminolevulinic acid photodynamic therapy（ALA-PDT） in the treatment of moderate-to-severe facial acne and take coresponing nursing measures. Methods From Oct 2014 to Jun 2015, eighty patients with facial moderate to severe acne were treated by topical 5% ALA-PDT.Then, 5% topical ALA was applied for 1-2 h under plastic film occlusion and exposed to 633 nm LED red light irradiation for 20 min, then cold spray for 20 min. After the treatment,these patients were advised to strictly avoid sunlight for48 h. Every 2 weeks of once treatment, a course of 3 or 4 times. Patients were followed up for 6 months. After treatment,the effec tiveness was evaluated. Results Among eighty patients with moderate-severe acne,53 cases（66.25%）were cured, 10 cases（12.50%） cases markedly improved,10 case（12.50%） were better, 7 cases（3.75%） were invalid.The total efficacy was 91.25%. Thirty-two patients complainted local side effects, such as erythema and pain, which was mild and resolved within several days without any special treatments. Conclusion 5% topical ALA-PDT is effective for treating the moderate to severe acne, without severe side effects.

关 键 词：痤疮 光动力 治疗 护理 

分 类 号：R758.733[医药卫生—皮肤病学与性病学] R473.75[医药卫生—临床医学]