比较甲基强的松龙早期短程冲击疗法与地塞米松治疗小儿重症病毒性脑炎的临床疗效  

Comparison of Clinical Curative Effect of Early Short-Course Pulse Therapy of Methylprednisolone and Dexamethasone in Treatment of Children with Severe Viral Encephalitis

作　　者：苏军[1] 王琪[1] 马洁[1] 

机构地区：[1]郑州市儿童医院内科监护室,河南郑州450053

出　　处：《中外医疗》2016年第4期118-119,共2页China & Foreign Medical Treatment

摘　　要：目的对比分析甲基强的松龙早期短程冲击疗法与地塞米松治疗小儿重症病毒性脑炎的临床疗效。方法随机选取该院2013年3月—2015年3月收治的50例重症病毒性脑炎患儿作为研究对象,随机分为观察组25例,对照组25例,观察组采用甲基强的松龙早期短程冲击疗法,对照组采用地塞米松治疗,对比两组临床疗效。结果观察组总有效率达到了92%,而对照组为88%,两组相比差异具有统计学意义,但观察组症状消失和住院时间显著少于对照组(P<0.05)。结论甲基强的松龙早期短程冲击疗法治疗小儿重症病毒性脑炎临床疗效好于地塞米松治疗,临床价值更高。Objective To compare and analyze the clinical curative effect of early short-course pulse therapy of methylprednisolone and dexamethasone in treatment of children with severe viral encephalitis. Methods 50 cases of children with severe viral encephalitis treated in our department from March 2013 to March 2015 were selected as the research object and randomly divided into two groups with 25 cases in each, the observation group were treated with early short-course pulse therapy of methylprednisolone, the control group were treated with dexamethasone, the clinical curative effect of the two groups was compared. Results The difference in the total effective rate between the observation group and the control group was not obvious（92% vs 88%）, the disappearance time of symptoms and length of stay in the observation group were obviously lower than those in the control group（P〈0.05）. Conclusion The clinical curative effect of early short-course pulse therapy of methylprednisolone in treatment of children with severe viral encephalitis is better than that of dexamethasone, and it is of higher clinical value.

关 键 词：病毒性脑炎 甲基强的松龙 地塞米松 冲击疗法 

分 类 号：R4[医药卫生—临床医学]