河北省保定市2004～2013年<15岁儿童乙型病毒性肝炎流行病学分析  

Epidemiological Analysis of Hepatitis B among Children Aged <15 Years in Baoding of Hebei Province,2004-2013

作　　者：马丽娜[1] 张玉玺[1] 左志平[1] 吴冰冰[1] 李淑芳[1] 曹丽霞[1] 张利[1] 

机构地区：[1]保定市疾病预防控制中心,河北保定071000

出　　处：《中国疫苗和免疫》2016年第1期76-79,共4页Chinese Journal of Vaccines and Immunization

摘　　要：目的分析保定市2004~2013年<15岁儿童乙型病毒性肝炎(乙肝)的流行病学特征,为预防控制乙肝提供参考。方法乙肝病例数据来源于中国免疫规划监测信息管理系统,采用描述性流行病学方法进行分析。结果2004~2013年报告<15岁儿童乙肝病例961例,年平均发病率为5.29/10万,各年发病率在0.24/10万~16.78/10万之间,总体呈下降趋势(x^2=653.58,P﹤0.001)。发病年龄主要集中9~14岁,发病率为10.6/10万。有乙肝疫苗(HepB)免疫史病例占41.94%,无免疫史和免疫史不详占58.06%。结论保定市<15岁儿童乙肝发病呈逐年下降趋势,发病年龄分布主要集中2002年HepB纳入免疫规划前的年龄段,应继续加强现有的控制乙肝免疫策略。Objective To determine the epidemiological characteristics of hepatitis B infection among children aged 〈 15 years in Baoding city, 2004-2013, and to provide evidence supporting prevention and control of hepatitis B. Methods Relevant hepatitis B data were collected from the China Immunization Program Monitoring Information Management System, and were analyzed through descriptive epidemiological methods. Results 961 hepatitis B cases among children aged 〈 15 years were reported in Baoding, 2004-2013, for an annual average incidence of 5.29 per 100 000 population. The incidence rates each year ranged from 0. 24 to 16.78 per 100 000 population, with a general decreasing trend （x2 = 653..58, P 〈0. 001 ）. Most cases occurred in children aged 9-14 years, for an incidence of 10. 6 per 100 000 pop- ulation. Cases with an immunization history of hepatitis B vaccine （HepB） accounted for 41.94% of in- fections, and cases with no or an unknown immunization history accounted for 58.06%. Conclusions The incidence of hepatitis B among children aged 〈 15 years in Baoding showed a decreasing trend year by year. Hepatitis B cases were seen most often among those born before HepB was included into the im- munization program in 2002. The existing immunization strategy for hepatitis B control should be strength- ened.

关 键 词：乙型病毒性肝炎 流行病学 分析 

分 类 号：R186[医药卫生—流行病学]